{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T19:00:25Z","timestamp":1782154825331,"version":"3.54.5"},"reference-count":72,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2006,5,15]],"date-time":"2006-05-15T00:00:00Z","timestamp":1147651200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2006,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The first cystic fibrosis (CF) scoring system was published in 1958. Since then, many other scoring systems were developed. Clinical parameters, details about statistical evaluations, and recent strategic uses of scores were identified. Several similar scores aiming to assess chronic illness severity (Shwachman\u2010Kulczycki score and a modification, Cooperman, Berneze\u2010score and the NIH score) have not been evaluated and are out of date, given the changing natural history of CF. Of the current scoring systems, the modified Shwachman score by Doershuk is perhaps most reliable for describing follow\u2010up studies. Scores designed for acute changes and short\u2010term evaluation were also developed. The modified Huang score may be useful in the prognostic evaluation of patients with end\u2010stage disease. It could also be used for discrimination of adult patients with differing disease severity and for longitudinal evaluation. Scores assessing pulmonary exacerbations could help provide consensus among clinicians regarding the need for intervention. Most of these scores require further evaluation. Although scores could provide an objective measure of disease severity, progression, need for and response to interventions, including value in selecting patients for lung transplantation and as an outcome measure for research studdies, no scoring system can fulfill all these objectives. Nevertheless, there is a need for the development of a modern day longitudinal score that is sensitive, valid and reproducible, to reflect the milder disease status of patients. Pediatr Pulmonol. 2006; 41: 602\u2013617. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.20376","type":"journal-article","created":{"date-parts":[[2006,5,15]],"date-time":"2006-05-15T16:25:34Z","timestamp":1147710334000},"page":"602-617","source":"Crossref","is-referenced-by-count":33,"title":["Clinical scoring systems in cystic fibrosis"],"prefix":"10.1002","volume":"41","author":[{"given":"Gaudenz M.","family":"Hafen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarath C.","family":"Ranganathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin F.","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip J.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,5,15]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1958.02060060008002"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132004000300016"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01314939"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.63.1.24"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00972431"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1542\/peds.91.2.488","article-title":"Wisconsin cystic fibrosis chest radiograph scoring system","volume":"91","author":"Weatherly MR","year":"1993","journal-title":"Pediatrics"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.49.9.860"},{"key":"e_1_2_1_9_2","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1177\/014107689709031S08","article-title":"Quality of life in cystic fibrosis","volume":"90","author":"Abbott J","year":"1997","journal-title":"J R Soc Med [Suppl]"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsg044"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(64)80152-9"},{"key":"e_1_2_1_12_2","first-page":"580","article-title":"A simplified cystic fibrosis scoring system (a preliminary report)","volume":"105","author":"Cooperman EM","year":"1971","journal-title":"Can Med Assoc J"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(73)80110-6"},{"key":"e_1_2_1_14_2","first-page":"417","article-title":"Relationship between clinical conditions, radiographic findings and pulmonary functions in patients with cystic fibrosis","volume":"34","author":"Kraemer R","year":"1979","journal-title":"Helv Paediatr Acta"},{"key":"e_1_2_1_15_2","first-page":"207","volume-title":"1,000 years of cystic fibrosis collected papers. 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