{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T21:07:39Z","timestamp":1781298459486,"version":"3.54.1"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,3,17]],"date-time":"2006-03-17T00:00:00Z","timestamp":1142553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2006,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Because <jats:italic>Haemophilus influenzae<\/jats:italic> type b (Hib) vaccination was added recently to most vaccination programs, no conclusive data on the relationship with atopic disorders are yet available. We sought to assess the risk of atopic disorders at ages 8\u201312 years associated with Hib vaccination in the first year of life, in addition to diphtheria\u2010tetanus\u2010pertussis\u2010inactivated poliomyelitis vaccination (DTP\u2010IPV) and other childhood vaccinations. Parents of 1,201 children attending Orthodox Reformed (Protestant) primary schools in The Netherlands returned questionnaires reporting data on vaccination status, atopic symptoms and physician\u2010diagnosed lifetime atopic disorders (asthma, hay fever, eczema, and food allergy), and possible confounders. This study was conducted within the framework of a larger study on the relationship between the DTP\u2010IPV and reported atopic disorders. The adjusted odds ratio of any atopic disorder (Hib\u2010vaccinated\/unvaccinated) was 1.09 (95% confidence interval (CI), 0.79\u20131.50). For asthma, hay fever, eczema, and food allergy, the results were, respectively, 0.89 (95% CI, 0.55\u20131.43), 0.94 (95% CI, 0.47\u20131.90), 1.09 (95% CI, 0.75\u20131.58), and 0.68 (95% CI, 0.38\u20131.19). In conclusion, in the Dutch population, there is no indication for a higher risk of reported physician\u2010diagnosed atopic disorders at primary schools age after Hib vaccination in the first year of life, in addition to other vaccinations. Pediatr Pulmonol. 2006; 41:463\u2013469. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.20397","type":"journal-article","created":{"date-parts":[[2006,3,17]],"date-time":"2006-03-17T22:46:46Z","timestamp":1142635606000},"page":"463-469","source":"Crossref","is-referenced-by-count":17,"title":["<i>Haemophilus influenzae<\/i> type b vaccination and reported atopic disorders in 8\u201312\u2010year\u2010old children"],"prefix":"10.1002","volume":"41","author":[{"given":"Roos M.D.","family":"Bernsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart W.","family":"Koes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan C.","family":"de Jongste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes C.","family":"van der Wouden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,3,17]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2004.02.033"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2004.09.021"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00039803"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20089"},{"key":"e_1_2_1_6_2","article-title":"The diphtheria tetanus pertussis poliomyelitis vaccination and reported atopic disorders in primary school children","author":"Bernsen RM","year":"2005","journal-title":"Vaccine"},{"key":"e_1_2_1_7_2","first-page":"387","article-title":"Vaccination against Haemophilus influenzae type B and atopy in East German schoolchildren","volume":"7","author":"Laubereau B","year":"2002","journal-title":"Eur J Med Res"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200206000-00004"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.95.08030483"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.2002.01254.x"},{"key":"e_1_2_1_11_2","first-page":"256","volume-title":"Lippincott Modern epidemiology","author":"Rothman K","year":"1998"},{"key":"e_1_2_1_12_2","unstructured":"Kerncijfers Vierpositie Postcodegebieden 1995 Centraal Bureau voor de Statistiek Voorburg\/Heerlen"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1086\/323342"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200312-1647OC"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.20397","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.20397","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T20:10:45Z","timestamp":1696623045000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.20397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,3,17]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["10.1002\/ppul.20397"],"URL":"https:\/\/doi.org\/10.1002\/ppul.20397","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,3,17]]}}}