{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:11:59Z","timestamp":1789179119284,"version":"build-2803163510"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,12,21]],"date-time":"2006-12-21T00:00:00Z","timestamp":1166659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2007,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim:<\/jats:title><jats:p>Only a limited number of studies, designed to establish normal values for sleep\u2010related respiratory variables in children, have been reported, and all are non\u2010European. The aim of this study was to expand the knowledge on normative data in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p>Subjects ranging from 6 to 16 years were recruited and underwent full polysomnography. Only subjects without sleep disordered breathing or other sleep problems as assessed by clinical history were included.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p>Sixty subjects were studied (\u3008age\u3009\u2009=\u200911.7\u2009\u00b1\u20092.6 years; 28 boys; \u3008relBMI\u3009\u2009=\u2009118.8\u2009\u00b1 30.6%). \u3008Central apnea index\u3009 was 0.85\u2009\u00b1\u20091.06 (range: 0.0\u20135.5). \u3008Obstructive apnea index\u3009 was 0.06\u2009\u00b1\u20090.16 (range: 0.0\u20130.9); 11 patients had a total of 31 obstructive apneas. Only five obstructive hypopneas were detected with \u3008obstructive apnea hypopnea index\u3009\u2009=\u20090.08\u2009\u00b1\u20090.17 (range: 0.0\u20130.9). \u3008Respiratory disturbance index\u3009 was 1.98\u2009\u00b1\u20091.39 (range: 0.1\u20137.2). \u3008SaO<jats:sub>2<\/jats:sub>\u3009 was 97.0\u2009\u00b1\u20090.6% (range: 96.0\u201398.0); \u3008SaO<jats:sub>2<\/jats:sub>nadir\u3009 was 91.8\u2009\u00b1\u20092.7% (range: 82.0\u201396.0); \u3008% of total sleep time with SaO<jats:sub>2<\/jats:sub>\u2009\u2265\u200995%\u3009 was 98.7\u2009\u00b1\u20092.1% (range: 90.8\u2013100.0); \u3008oxygen desaturation index\u3009 was 0.8\u2009\u00b1\u20090.9 (range: 0.0\u20134.9) and \u3008arousal index\u3009 was 6.1\u2009\u00b1\u20091.8 (range: 2.7\u201310.9). Snoring was detected in 15 patients (4 overweight subjects), with no difference in patient characteristics and sleep\u2010related respiratory variables between snorers and non\u2010snorers. Subjects in the overweight group (n\u2009=\u200922) had a lower SaO<jats:sub>2<\/jats:sub>nadir (90.8\u2009\u00b1\u20092.7 vs. 92.4\u2009\u00b1\u20092.6; <jats:italic>P<\/jats:italic>\u2009=\u20090.01) and a higher ODI (1.3\u2009\u00b1\u20091.3 vs. 0.4\u2009\u00b1\u20090.4; <jats:italic>P<\/jats:italic>\u2009=\u20090.0002) than their normal weight peers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p>Our data are in agreement with other non\u2010European studies, designed to establish normal values in children. Pediatr Pulmonol. 2007; 42:159\u2013167. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.20551","type":"journal-article","created":{"date-parts":[[2006,12,21]],"date-time":"2006-12-21T23:48:56Z","timestamp":1166744936000},"page":"159-167","source":"Crossref","is-referenced-by-count":113,"title":["Reference values for sleep\u2010related respiratory variables in asymptomatic European children and adolescents"],"prefix":"10.1002","volume":"42","author":[{"given":"S.L.","family":"Verhulst","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Schrauwen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Haentjens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Van Gaal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.A.","family":"De Backer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.N.","family":"Desager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,12,21]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.153.2.8564147"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.6.1930"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1112"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.4.963"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.68.3.360"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.5_Pt_1.1235"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.168.12.954"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.3.872"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20236"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1067"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(89)80738-3"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0496(199603)21:3<176::AID-PPUL5>3.0.CO;2-O"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950160208"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0496(200004)29:4<284::AID-PPUL8>3.0.CO;2-D"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.88.12.1043"},{"key":"e_1_2_1_17_2","article-title":"Sleep\u2010disordered breathing in overweight and obese children and adolescents: Prevalence, characteristics and the role of fat distribution","author":"Verhulst SL","journal-title":"Arch Dis Child"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.5.9809079"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2003.28"},{"key":"e_1_2_1_20_2","first-page":"443","article-title":"Increasing incidence of childhood obesity","volume":"1","author":"Laron Z","year":"2004","journal-title":"Pediatr Endocrinol Rev"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2869.2004.00432.x"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(84)80348-0"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)36806-7"},{"key":"e_1_2_1_24_2","unstructured":"HauspieR RoelantsM.Growth Charts Flanders 2004. 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