{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T18:13:38Z","timestamp":1758824018989},"reference-count":29,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2009,6,4]],"date-time":"2009-06-04T00:00:00Z","timestamp":1244073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2009,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The Sensormedics\u00ae 3100A (Cardinal Health, Dublin, OH) (HFOV) and the Bronchotron\u00ae (Percussionaire, Sandpoint, ID) (HFPV) are high\u2010frequency ventilation devices used to support neonatal respiratory failure; however, a comparison of the devices, with respect to gas exchange at similar ventilator settings, has not been previously studied. Thus, we compared the ability of HFOV to that of HFPV to provide oxygenation and ventilation during acute lung injury in a newborn animal model. Using a saline lung lavage model, 12 neonatal piglets were randomized to initial support with either the HFOV or HFPV with settings adjusted to achieve PaCO<jats:sub>2<\/jats:sub> of 45\u201360 mmHg. After stabilization, ventilator settings and arterial blood gases were serially recorded for 30 min. Animals were then crossed over to the alternative device set to deliver the same V<jats:sub>t<\/jats:sub>, MAP, and F for an additional 30 min with the same parameters recorded. We found that the \u0394P needed to generate adequate V<jats:sub>t<\/jats:sub> on HFPV (35\u2009\u00b1\u20097 cmH<jats:sub>2<\/jats:sub>O) trended higher versus HFOV (31\u2009\u00b1\u20097 cmH<jats:sub>2<\/jats:sub>O <jats:italic>P<\/jats:italic>\u2009=\u20090.09) when the devices were matched for V<jats:sub>t<\/jats:sub>, F, and MAP. No significant differences in ventilation (PaCO<jats:sub>2<\/jats:sub>\u2009=\u200950\u2009\u00b1\u200910.7 mmHg vs. 46\u2009\u00b1\u200910 mmHg, <jats:italic>P<\/jats:italic>\u2009=\u20090.22) or oxygenation (PaO<jats:sub>2<\/jats:sub>\u2009=\u2009150\u2009\u00b1\u200976 mmHg vs. 149\u2009\u00b1\u2009107 mmHg, <jats:italic>P<\/jats:italic>\u2009=\u20090.57) between the devices were found. We conclude that HFPV ventilates and oxygenates as well as HFOV at equivalent ventilator settings. HFPV may require larger \u0394P's to generate equivalent V<jats:sub>t<\/jats:sub>. Pediatr Pulmonol. 2009; 44:693\u2013700. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.21041","type":"journal-article","created":{"date-parts":[[2009,6,4]],"date-time":"2009-06-04T18:47:37Z","timestamp":1244141257000},"page":"693-700","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of the Sensormedics\u00ae 3100A and Bronchotron\u00ae transporter in a neonatal piglet ARDS model"],"prefix":"10.1002","volume":"44","author":[{"given":"Stephen E.","family":"Messier","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"DiGeronimo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert K.","family":"Gillette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,6,4]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"CD0000104","article-title":"Elective high frequency oscillatory ventilation versus conventional ventilation for acute pulmonary dysfunction in premature infants","volume":"3","author":"Henderson\u2010Smart DJ","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2004.07.002"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81098-4"},{"key":"e_1_2_1_5_2","first-page":"157","volume-title":"ECMO: Extracorporeal cardiopulmonary support in critical care","author":"DiGeronimo RJ","year":"2005"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1542\/peds.89.1.5","article-title":"Prospective randomized comparison of high frequency oscillatory and conventional ventilation in respiratory distress syndrome","volume":"89","author":"Clark RH","year":"1991","journal-title":"Pediatrics"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)83548-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1542\/peds.98.6.1044","article-title":"The Provo multicenter early high\u2010frequency oscillatory ventilation trial: Improved pulmonary and clinical outcome in respiratory distress syndrome","volume":"98","author":"Gerstmann DR","year":"1996","journal-title":"Pediatrics"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001340050789"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1542\/neo.7-5-e234"},{"key":"e_1_2_1_11_2","first-page":"129","article-title":"A cart to provide high frequency jet ventilation during transport of neonates","volume":"37","author":"Scuderi J","year":"1992","journal-title":"Respir Care"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211799"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1891\/0730-0832.26.3.167"},{"key":"e_1_2_1_14_2","volume-title":"Bronchotron\u2014I. 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