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There are many respiratory complications associated with OI including pneumonia, the most common cause of mortality in the severe forms of the disease. We present a case of an infant with OI (type III\/IV) and significant tracheobronchomalacia who had required multiple hospitalizations for recurrent atelectasis and respiratory failure in the setting of acute respiratory infections. External chest percussion and vibration were avoided because of the risk of rib fractures. intrapulmonary percussive ventilation (IPV) was initiated during an acute illness with good effect, and continued successfully after discharge from hospital. We conclude that IPV represents a safe and effective alternative to airway clearance in infants with OI. Pediatr Pulmonol. 2009; 44:1151\u20131154. \u00a92009 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.21112","type":"journal-article","created":{"date-parts":[[2009,10,12]],"date-time":"2009-10-12T19:50:06Z","timestamp":1255377006000},"page":"1151-1154","source":"Crossref","is-referenced-by-count":11,"title":["Use of intrapulmonary percussive ventilation (IPV) in the management of pulmonary complications of an infant with osteogenesis imperfecta"],"prefix":"10.1002","volume":"44","author":[{"given":"Gustavo","family":"Nino","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"McNally","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura 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