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We report the cases of two children, presenting with isolated central sleep apnea leading to a diagnosis of type I Chiari malformation. Surgical treatment resulted in a dramatic improvement in respiratory parameters during sleep, both clinically and on polysomnography.<\/jats:p><jats:p>We discuss this uncommon presentation of type I Chiari malformation and suggest that it be considered in the differential diagnosis of central sleep apnea in children, as posterior fossa decompression may lead to significant clinical improvement. Pediatr Pulmonol. 2010;45:1141\u20131144. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.21294","type":"journal-article","created":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T15:30:39Z","timestamp":1284651039000},"page":"1141-1144","source":"Crossref","is-referenced-by-count":32,"title":["Isolated central sleep apnea in type I Chiari malformation: Improvement after surgery"],"prefix":"10.1002","volume":"45","author":[{"given":"Jessica","family":"Spence","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Pasterkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,9,16]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2003.99.2.0291"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.3171\/PED\/2008\/2\/9\/179"},{"key":"e_1_2_5_4_2","first-page":"5S156","article-title":"Pathologies de la charni\u00e8re cervical et apn\u00e9es du sommeil","volume":"157","author":"Reybet\u2010Degat O","year":"2001","journal-title":"Rev Neurol"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2006.108779"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/23.5.1f"},{"key":"e_1_2_5_7_2","first-page":"929","article-title":"Sleep apnea and the Arnold\u2010Chiarimalformation","volume":"132","author":"Balk RA","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(99)00004-0"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2008.05.017"},{"key":"e_1_2_5_10_2","first-page":"277","article-title":"Central sleep apnea syndrome as the first sign of type I Chiari malformation","volume":"68","author":"Miralbes Terraza S","year":"2008","journal-title":"An Pediatr (Barc)"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1023948921381"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000191394.53786.62"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.108.2.425"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.95.5.1064"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2004.10.008"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.21294","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.21294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,9]],"date-time":"2023-10-09T16:53:30Z","timestamp":1696870410000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.21294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9,16]]},"references-count":14,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["10.1002\/ppul.21294"],"URL":"https:\/\/doi.org\/10.1002\/ppul.21294","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,9,16]]}}}