{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T17:17:37Z","timestamp":1773249457589,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Research Grants Council Earmarked Grant","award":["CUHK 4512\/06M"],"award-info":[{"award-number":["CUHK 4512\/06M"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Indoor aeroallergen exposures increased asthma symptoms in Caucasians, but their determinants and relationship to asthma and allergy in Asians are unclear. This study investigated exposures to cat, cockroach, and <jats:italic>Blomia tropicalis<\/jats:italic> allergens in 115 Hong Kong families with asthmatic children. Patients underwent exhaled nitric oxide and spirometric measurements. Home visits were made within 2 weeks during which parents completed a standardized questionnaire. Fel d 1, Bla g 2, and Blo t 5 in dust samples collected from patients' mattresses, bedroom floors, and living room floors were measured by immunoassays. These aeroallergens were only detectable in some homes (38\u201355% for Fel d 1; 9\u201321% for Bla g 2, and 7\u201314% for Blo t 5). The presence of cat and\/or dog was a strong determinant for Fel d 1 in all indoor sites. The timing and frequency of bedding change was associated with Bla g 2 levels, whereas the timing of bedroom floor cleaning was a consistent factor for Blo t 5 levels. Asthmatic children in families with high allergen exposure were more likely to have \u22654 wheezing attacks in preceding 12 months and exercise\u2010induced wheezing than those with normal allergen exposure (<jats:italic>P<\/jats:italic>\u2009=\u20090.051 and 0.030, respectively). Mattress levels of all three allergens were also associated with severity of several allergy symptoms (<jats:italic>P<\/jats:italic>\u2009=\u20090.025\u20130.005). None of these aeroallergens correlated with exhaled nitric oxide and spirometric parameters. This study identifies determinants for cat, cockroach, and <jats:italic>B. tropicalis<\/jats:italic> levels in Hong Kong families with asthmatic children. These exposures are associated with severity of allergy symptoms. Pediatr. Pulmonol. 2011; 46:632\u2013639. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ppul.21391","type":"journal-article","created":{"date-parts":[[2011,6,3]],"date-time":"2011-06-03T12:29:47Z","timestamp":1307104187000},"page":"632-639","source":"Crossref","is-referenced-by-count":15,"title":["Domestic exposure to aeroallergens in Hong Kong families with asthmatic children"],"prefix":"10.1002","volume":"46","author":[{"given":"Ting F.","family":"Leung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun S.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iris H.S.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edmund","family":"Yung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hing 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