{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:44:54Z","timestamp":1790304294512,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2011,5,27]],"date-time":"2011-05-27T00:00:00Z","timestamp":1306454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the clinical role of flexible bronchoscopy (FB) in pediatric and neonatal intensive care units (ICUs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>A retrospective review of all patients receiving FB procedures between January 2005 and December 2009.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Pediatric and neonatal ICUs of a tertiary care multi\u2010disciplinary teaching hospital located in northern Taiwan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients<\/jats:title><jats:p>A total of 358 ICU patients (223 males) who received 725 FB procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>The medical records were reviewed and analyzed. Mean age for the first time FB was 35.7 (\u00b148.9 SD) months old and 68.2% of them were &lt;3 years old. Among them, unexplained retraction or tachypnea (32.0%) and stridor (20.1%) were the two leading indications for FB. The positive finding rate of FB was 87.2%, with airway malacia (47.8%) being the most common, especially in patients &lt;3 years old. Positive lesion sites were approximately equally distributed between the upper (51.1%) and lower (50.6%) airways. Concomitant findings in the esophagus were found in 15.4% of the patients. There were 518 interventional FBs (71.4%, 518\/725 procedures) which were performed on 201 (56.1%, 201\/358) patients; FB\u2010aided endotracheal intubation (180\/518, 34.7%) and laser therapy (109\/518, 21.0%) were the two leading techniques used. No patient suffered from any long\u2010term complications or mortality associated with the FB procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>FB is a safe and valuable diagnostic and therapeutic tool for patients in pediatric and neonatal ICUs. Pediatr. Pulmonol. 2011; 46:1031\u20131037. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.21464","type":"journal-article","created":{"date-parts":[[2011,5,27]],"date-time":"2011-05-27T17:44:16Z","timestamp":1306518256000},"page":"1031-1037","source":"Crossref","is-referenced-by-count":45,"title":["Flexible bronchoscopy as a valuable diagnostic and therapeutic tool in pediatric intensive care patients: A report on 5 years of experience"],"prefix":"10.1002","volume":"46","author":[{"given":"Yu\u2010Yun","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Jue","family":"Soong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Sheng","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei\u2010Chen","family":"Tsao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia\u2010Feng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Jy","family":"Jeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,5,27]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.89.5.673"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.97.1.199"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1099-0496(200102)31:2<150::AID-PPUL1024>3.0.CO;2-6"},{"key":"e_1_2_7_5_2","first-page":"338","article-title":"The application of modified mini\u2010flexible\u2010fiberoptic endoscopy in pediatric practice","volume":"56","author":"Soong WJ","year":"1995","journal-title":"J Chin Med Assoc"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.03.00084102"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008480-200206000-00009"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0b013e3282ff631e"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.73.5_Supplement.737"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)34645-4"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1442-200X.2003.01785.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.93.3.556"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.66.12.1383"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.4.1353"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-006-0351-y"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20910"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.00113202"},{"key":"e_1_2_7_18_2","unstructured":"SoongWJ JengMJ LeeYS HwangB YehTF.Continuous nasopharyngeal oxygen with supplemental pinch nose ventilation for pediatric flexible bronchoscopy\u2014A new method of oxygenation and ventilation. Pediatric Academic Society Annular Meeting; 2004:3395."},{"key":"e_1_2_7_19_2","unstructured":"SoongWJ TsaoPC ChangHL LeeYS JengMJ KouYR HwangH.Tracheobronchial expandable metallic stent placement solely by flexible endoscopy in children. American Thoracic Society Annular Meeting; 2005 May 23:A557."},{"key":"e_1_2_7_20_2","unstructured":"TsaoPC SoongWJ JengMJ ChangHL LeeYS KouYR HwangB.Flexible bronchoscopic diagnosis and removal of airway foreign bodies in children. American Thoracic Society Annular Meeting; 2005 May 23:A472."},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2010.08.019"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2004.04.001"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1726-4901(08)70004-2"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2011.03.016"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e3181aba8c1"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.02072001"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/00130478-200204000-00015"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.02.010"},{"key":"e_1_2_7_29_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.69.5_Spec_No.533"},{"key":"e_1_2_7_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950160402"},{"key":"e_1_2_7_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3181bc5b00"},{"key":"e_1_2_7_32_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e3181bc5a85"},{"key":"e_1_2_7_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31819372ea"},{"key":"e_1_2_7_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(84)80354-1"},{"key":"e_1_2_7_35_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20139"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.21464","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.21464","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T09:47:33Z","timestamp":1700560053000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.21464"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,27]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,10]]}},"alternative-id":["10.1002\/ppul.21464"],"URL":"https:\/\/doi.org\/10.1002\/ppul.21464","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,27]]}}}