{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T06:38:07Z","timestamp":1791095887998,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2011,10,17]],"date-time":"2011-10-17T00:00:00Z","timestamp":1318809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2012,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Persistent lung atelectasis is difficult to treat and perfluorochemical (PFC) liquid may be an option for bronchioalveolar lavage (BAL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Case report<\/jats:title><jats:p>A 4\u2010year\u2010old girl with spinal muscle atrophy was admitted in respiratory failure. On admission, the X\u2010ray confirmed the persistence of total right\u2010sided lung atelectasis, which had been present for 14 months. She was endotracheally intubated and ventilated from the day of admission. BAL with normal saline was performed twice without improvement. Following failed extubation and being dependent on continuous respiratory support, a trial of BAL using PFC liquid (Perfluorodecalin HP) was carried out. The PFC was delivered through the endotracheal tube on three consecutive days. A loading dose of 3\u2009ml\/kg was administered, followed by a varying dose in order to more effectively lavage the lungs. She tolerated the procedure well the first 2 days, although there were no clinical signs of improvement in the atelectasis. Intentionally, higher inflation pressures were applied after PFC instillation on day 3. Chest X\u2010ray then showed hazy infiltrates on her left lung and she required more ventilatory support. However, lung infiltrates cleared over the next 3 days. A tracheotomy was done 6 days after the last PFC instillation. She had a slow recovery and was successfully decanulated. Clinical improvement of lung function was seen including less need of BiPAP and oxygen. A chest CT scan showed then functional lung tissue appearing in the previous total atelectatic right lung.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Lavage with PFC can safely be performed with a therapeutic effect in a child with unilateral total lung atelectasis. Pediatr Pulmonol. 2012; 47:415\u2013419. \u00a9 2011 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.21565","type":"journal-article","created":{"date-parts":[[2011,10,17]],"date-time":"2011-10-17T15:12:44Z","timestamp":1318864364000},"page":"415-419","source":"Crossref","is-referenced-by-count":8,"title":["Perfluorodecalin lavage of a longstanding lung atelectasis in a child with spinal muscle atrophy"],"prefix":"10.1002","volume":"47","author":[{"given":"Thore","family":"Henrichsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paal HH","family":"Lindenskov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas H","family":"Shaffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth JV","family":"Loekke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drude","family":"Fugelseth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolf","family":"Lindemann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,10,17]]},"reference":[{"key":"e_1_2_7_2_2"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.065961"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/prrv.2000.0059"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2261-1"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200005000-00067"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2262-0"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2010.02.006"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc3766"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.97.2.435"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.62.5_Supplement.70S"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1159\/000215729"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20784"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001340100904"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949610501104"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PCC.0000282757.25347.6C"},{"key":"e_1_2_7_17_2","first-page":"163","article-title":"Atelectasis of the lung: bronchoscopic lavage with acetylcysteine. 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