{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T18:55:42Z","timestamp":1771872942883,"version":"3.50.1"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,3,19]],"date-time":"2012-03-19T00:00:00Z","timestamp":1332115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and Aims<\/jats:title><jats:p>Immature lungs of preterm infants are particularly prone to overdistension from mechanical ventilation or continuous positive airway pressure. In these infants a localized pulmonary emphysema (PE) can develop. Conventional therapy regimens to resolve this process sometimes fail and especially in the case of bullous emphysema (BE) invasive procedures such as surgical resection of the affected lobe ultimately may be required. In the past few years we have applied selective one\u2010sided lung ventilation, a nearly forgotten therapeutic option, in these infants with acquired BE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Medical charts of preterm infants in two Divisions of Neonatology, born between 1993 and 2010 with acquired BE treated with selective one\u2010sided ventilation were reviewed. Gestational age, clinical presentation, course of disease, associated treatment, duration of ventilation and outcome of one\u2010sided lung ventilation are recorded. Therapy was deemed successful if thereafter chest X\u2010ray showed a permanent resolution of the BE and, in case of BPD, lung appearance was comparable to a grade\u2009&lt;\u2009III according to Weinstein [Weinstein et al. Pediatr Pulmonol 1994; 18: 284\u2013289].<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, nine preterm infants with a gestational age between 24 and 35 weeks and a birth weight between 500 and 3,170\u2009g underwent one\u2010sided lung ventilation. This intervention was started between day 12 and day 35 after birth and was continued for 24\u2009hr to 7 days. In three cases selective intubation was performed on the left side. Two patients needed a second course of one\u2010sided ventilation and one had three courses. Therapy was successful in seven patients, who had no recurrence of BE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Selective one\u2010sided intubation is technically challenging, in particular for the left bronchus, but seems to be feasible and helpful. If during selective intubation the affected lung lobe shows complete atelectasis for more than 48\u2009hr the overdistension of airways probably will permanently resolve. Pediatr Pulmonol. 2013; 48:14\u201319. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.22530","type":"journal-article","created":{"date-parts":[[2012,3,19]],"date-time":"2012-03-19T21:09:22Z","timestamp":1332191362000},"page":"14-19","source":"Crossref","is-referenced-by-count":13,"title":["Selective unilateral lung ventilation in preterm infants with acquired bullous emphysema: A series of nine cases"],"prefix":"10.1002","volume":"48","author":[{"given":"Andr\u00e9","family":"Jakob","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Bender","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Henschen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Saueressig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Uhl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Kr\u00fcger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Franck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Hentschel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,3,19]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/00313028909059539"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.01.071"},{"key":"e_1_2_5_4_2","first-page":"756","article-title":"Surfactant replacement therapy at birth: final analysis of a clinical trial and comparisons with similar trials","volume":"82","author":"Kendig JW","year":"1988","journal-title":"Pediatrics"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1542\/peds.87.3.377","article-title":"Bovine surfactant replacement therapy in neonates of less than 30 weeks' gestation: a randomized controlled trial of prophylaxis versus treatment","volume":"87","author":"Dunn MS","year":"1991","journal-title":"Pediatrics"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.161.2.3763899"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)81046-7"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.180.327"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1159\/000013957"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1038498"},{"key":"e_1_2_5_11_2","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1542\/peds.68.4.510","article-title":"Unilateral pulmonary interstitial emphysema: a surgical approach to treatment","volume":"68","author":"Levine DH","year":"1981","journal-title":"Pediatrics"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3468(84)80256-0"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-999867"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950180504"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80282-0"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(90)90343-8"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-993880"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10054"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-870206"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9592.2006.02044.x"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80525-8"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.63.3.313"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-007-0597-8"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.22530","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.22530","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T12:00:23Z","timestamp":1696680023000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.22530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,19]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1002\/ppul.22530"],"URL":"https:\/\/doi.org\/10.1002\/ppul.22530","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,19]]}}}