{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:35:07Z","timestamp":1791866107206,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,3,26]],"date-time":"2013-03-26T00:00:00Z","timestamp":1364256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"none reported"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe lung manifestations in MPO\u2010ANCA associated vasculitides in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively reviewed the medical records of patients with MPO\u2010ANCA associated vasculitis, who were followed in two pediatric nephrology departments from January 2000 to December 2010.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve patients were identified with MPO\u2010ANCA over the study period. Their median age (IQR) at diagnosis was 10.5 (6.3\u201312.0) years, and their median duration of follow\u2010up was 4.8 (1.2\u20137.5) years. Only five of them had pulmonary involvement with diffuse alveolar hemorrhage. Lung involvement was inaugural for four of five children. One child with severe chronic respiratory disease and renal failure died after 6 years of disease progression. Pulmonary function tests were available for 10 children. They were within normal ranges in four of five patients without clinical lung manifestations, and no significant impairment was observed in children with pulmonary complications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Diffuse alveolar hemorrhage complicates 40% of cases of MPO\u2010ANCA associated vasculitides in children with renal involvement. After an acute potentially severe phase, a complete recovery without significant functional impairment was observed in four of five affected children. <jats:bold>Pediatr Pulmonol. 2014; 49:285\u2013290.<\/jats:bold> \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.22793","type":"journal-article","created":{"date-parts":[[2013,3,26]],"date-time":"2013-03-26T15:16:10Z","timestamp":1364310970000},"page":"285-290","source":"Crossref","is-referenced-by-count":12,"title":["Lung manifestations in MPO\u2010ANCA associated vasculitides in children"],"prefix":"10.1002","volume":"49","author":[{"given":"Salma","family":"Ben Ameur","sequence":"first","affiliation":[{"name":"Pneumologie P\u00e9diatrique, Necker, AP\u2010HP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Niaudet","sequence":"additional","affiliation":[{"name":"N\u00e9phrologie P\u00e9diatrique, Necker, AP\u2010HP Paris France"},{"name":"Universit\u00e9 Paris\u2010Descartes Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Baudouin","sequence":"additional","affiliation":[{"name":"N\u00e9phrologie P\u00e9diatrique, Robert Debr\u00e9 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel Le.","family":"Bourgeois","sequence":"additional","affiliation":[{"name":"Pneumologie P\u00e9diatrique, Necker, AP\u2010HP Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Houdouin","sequence":"additional","affiliation":[{"name":"Pneumologie P\u00e9diatrique, Robert Debr\u00e9 Paris France"},{"name":"Universit\u00e9 Paris\u2010Diderot Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Delacourt","sequence":"additional","affiliation":[{"name":"Pneumologie P\u00e9diatrique, Necker, AP\u2010HP Paris France"},{"name":"Universit\u00e9 Paris\u2010Descartes Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Hadchouel","sequence":"additional","affiliation":[{"name":"Pneumologie P\u00e9diatrique, Necker, AP\u2010HP Paris France"},{"name":"Universit\u00e9 Paris\u2010Descartes Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,3,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)83482-1"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2011.04.002"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.111352"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-011-0459-0"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-012-2198-5"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5964.166"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00034805"},{"key":"e_1_2_5_9_1","first-page":"184S","article-title":"Compilation of reference values for lung function measurements in children","volume":"4","author":"Quanjer PH","year":"1989","journal-title":"Eur Respir J Suppl"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0b013e3181b59581"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.2165\/00126839-200708010-00003"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-005-2063-x"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-006-0028-3"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200511-120JH"},{"key":"e_1_2_5_15_1","first-page":"S48","article-title":"Respiratory system involvement in systemic vasculitides","volume":"24","author":"Manganelli P","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_5_16_1","first-page":"144","article-title":"Necrotizing alveolar capillaritis in autopsy cases of microscopic polyangiitis. 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