{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:56:27Z","timestamp":1764996987849},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T00:00:00Z","timestamp":1373414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Erasmus Medical Center, the Erasmus University Rotterdam, the Netherlands Organization for Health Research and Development"},{"name":"Europe Container Terminals"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To assess the relationship between physical activity in second year of life and respiratory symptoms during the pre\u2010school period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was embedded in the Generation R Study, a large prospective birth\u2010cohort study in Rotterdam, the Netherlands. Physical activity was measured in the second year of life by an Actigraph accelerometer in a subgroup of 347 children (182 boys, 165 girls; mean age 25.1 months) and data were expressed as counts per 15\u2009sec in categories: light activity (302\u2013614\u2009counts\/15\u2009sec), moderate activity (615\u20131,230\u2009counts\/15\u2009sec), and vigorous activity (\u22651,231\u2009counts\/15\u2009sec). Respiratory symptoms were assessed by the International Study of Asthma and Allergies in Childhood Questionnaire in the third and fourth year of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Physical activity levels were not associated with wheezing symptoms in the third and fourth year of life (OR: 0.98; 95% CI: 0.92\u20131.05 and OR: 0.99; 95% CI: 0.92\u20131.07 for total activity, respectively), nor associated with shortness of breath symptoms (OR: 0.98; 95% CI: 0.92\u20131.05 and OR 1.03; 95% CI: 0.96\u20131.11 for total activity, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These results suggest that physical activity may not play an important role in the development of respiratory symptoms in pre\u2010school children. <jats:bold>Pediatr Pulmonol. 2014; 49:36\u201342.<\/jats:bold> \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.22839","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T12:01:26Z","timestamp":1373457686000},"page":"36-42","source":"Crossref","is-referenced-by-count":7,"title":["Physical activity and respiratory symptoms in children: The generation R study"],"prefix":"10.1002","volume":"49","author":[{"given":"Lisa M.","family":"Driessen","sequence":"first","affiliation":[{"name":"The Generation R Study Group Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Pediatrics Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica C.","family":"Kiefte\u2010de Jong","sequence":"additional","affiliation":[{"name":"The Generation R Study Group Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Pediatrics Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent W.V.","family":"Jaddoe","sequence":"additional","affiliation":[{"name":"The Generation R Study Group Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Pediatrics Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Epidemiology Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert","family":"Hofman","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hein","family":"Raat","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johan C.","family":"de Jongste","sequence":"additional","affiliation":[{"name":"Department of Pediatrics\/Respiratory Medicine Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henriette A.","family":"Moll","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,7,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"944","DOI":"10.3390\/medicina44120118","article-title":"Time trends in the prevalence of asthma and allergy among 6\u20137\u2010year old children. 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