{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T12:48:41Z","timestamp":1756385321931},"reference-count":38,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T00:00:00Z","timestamp":1395792000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label \/><jats:p>Toxic epidermal necrolysis (TEN) is a rare and potentially fatal mucocutaneous condition that may affect both children and adults. TEN mortality rates vary greatly between both patient populations, but multisystem involvement is common. Management presents many challenges as there is no specific therapy for TEN, and patients often require the expertise of burn units. We report a child who survived TEN with multisystem involvement including the rare but life threatening occurrence of a pulmonary air\u2010leak syndrome while also reviewing controversies surrounding TEN's pathophysiology, sequelae, and multidisciplinary approach to management. <jats:bold>Pediatr Pulmonol. 2014; 49:E130\u2013E134.<\/jats:bold> \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.22908","type":"journal-article","created":{"date-parts":[[2014,3,26]],"date-time":"2014-03-26T10:30:48Z","timestamp":1395829848000},"source":"Crossref","is-referenced-by-count":6,"title":["An atypical presentation of pulmonary air\u2010leak syndrome and multisystem toxic epidermal necrolysis"],"prefix":"10.1002","volume":"49","author":[{"given":"Joseph T.","family":"Ellenburg","sequence":"first","affiliation":[{"name":"Department of Pediatric Pulmonology University of Mississippi Medical Center Jackson Mississippi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"David","family":"Josey","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology University of Mississippi Medical Center Jackson Mississippi"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61112-X"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1001\/archderm.1990.01670250043005","article-title":"Toxic epidermal necrolysis (Lyell syndrome): incidence and drug etiology in France","volume":"126","author":"Roujeau JC","year":"1990","journal-title":"Arch 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