{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T13:52:07Z","timestamp":1789480327737,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,2,16]],"date-time":"2014-02-16T00:00:00Z","timestamp":1392508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>Primary endobronchial tumors are rare in children and they include a broad spectrum of lesions. The aim of this study was to determine the characteristic features, treatments and outcomes of these tumors. We report a retrospective analysis of all patients treated for endobronchial tumor in nine French hospitals between 1990 and 2010 and a comparison of the results with those reported in the medical literature.<\/jats:p><jats:p>Twelve tumors were reported: five low grade muco epidermoid carcinomas, two inflammatory myofibroblastic tumors, two hemangiomas, one anaplastic large cell lymphoma, one carcinoid tumor, and one juvenile xanthogranuloma. The mean age of the patients was 7.5\u2009\u00b1\u20093.5 years. The most common sign revealing the disease was persistent atelectasis or recurrent pneumonia (eight cases). The other revealing signs were a persistent bronchospasm (three cases) and hemoptysis (one case). The clinical presentation, biology, serum tumor markers, and chest X\u2010ray abnormalities were not specific to a particular histological diagnosis. Chest CT scan revealed the presence of an endobronchial tumor in 11 cases. Nine tumors could be diagnosed from a biopsy obtained by video endoscopy. Complete surgical resection was performed in seven patients. Bronchoscopic removal was performed in five cases and was successful in three. There were no deaths.<\/jats:p><jats:p>Endobronchial tumors are rare in childhood and their histology is diverse. Chest CT scan and per\u2010endoscopic endobronchial biopsies are required for diagnosis, when possible. Surgical or endoscopic treatment should be discussed by a multidisciplinary team. Despite the multiple etiologies, the prognosis of these tumors is good if diagnosis is early and if resection is complete. Long\u2010term recurrences have been described, so long\u2010term follow\u2010up of these children is recommended. <jats:bold>Pediatr Pulmonol. 2014; 49:E121\u2013E125.<\/jats:bold> \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.22987","type":"journal-article","created":{"date-parts":[[2014,2,17]],"date-time":"2014-02-17T11:25:35Z","timestamp":1392636335000},"source":"Crossref","is-referenced-by-count":33,"title":["Characteristics of endobronchial primitive tumors in children"],"prefix":"10.1002","volume":"49","author":[{"given":"E.","family":"Eyssartier","sequence":"first","affiliation":[{"name":"Service de Chirurgie P\u00e9diatrique Visc\u00e9rale Urologique et Plastique, Br\u00fbl\u00e9s H\u00f4pital Gatien de Clocheville CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Ang","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Sp\u00e9cialit\u00e9s P\u00e9diatriques H\u00f4pital Gatien de Clocheville CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bonnemaison","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Sp\u00e9cialit\u00e9s P\u00e9diatriques H\u00f4pital Gatien de Clocheville CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Gibertini","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Sp\u00e9cialit\u00e9s P\u00e9diatriques H\u00f4pital Gatien de Clocheville CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Diot","sequence":"additional","affiliation":[{"name":"Service de Pneumologie H\u00f4pital Bretonneau CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Carpentier","sequence":"additional","affiliation":[{"name":"Service de Radiologie et Imagerie M\u00e9dicale H\u00f4pital Gatien de Clocheville CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Chantepie","sequence":"additional","affiliation":[{"name":"Unit\u00e9 de Sp\u00e9cialit\u00e9s P\u00e9diatriques H\u00f4pital Gatien de Clocheville CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.D.","family":"Leclair","sequence":"additional","affiliation":[{"name":"D\u00e9partement de Chirurgie P\u00e9diatrique H\u00f4pital M\u00e8re\u2010Enfant CHU de Nantes Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Brouard","sequence":"additional","affiliation":[{"name":"Service de P\u00e9diatrie m\u00e9dicale CHU\u2014H\u00f4pital Clemenceau Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Boutard","sequence":"additional","affiliation":[{"name":"Unit\u00e9 d'Oncologie P\u00e9diatrique CHU\u2014H\u00f4pital Clemenceau Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Deneuville","sequence":"additional","affiliation":[{"name":"Service de P\u00e9diatrie CHU\u2014H\u00f4pital\u2010Sud Rennes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Marie\u2010Cardine","sequence":"additional","affiliation":[{"name":"Service d'Oncologie P\u00e9diatrique Pavillon de P\u00e9diatrie CHU Ch Nicolle Rouen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Lardy","sequence":"additional","affiliation":[{"name":"Service de Chirurgie P\u00e9diatrique Visc\u00e9rale Urologique et Plastique, Br\u00fbl\u00e9s H\u00f4pital Gatien de Clocheville CHRU de Tours Tours France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-005-1740-x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830201)51:3<492::AID-CNCR2820510322>3.0.CO;2-W"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/jpsu.2003.50195"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(97)00185-X"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2011.153"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.5858\/2008-132-1079-PAMLTI"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(93)90147-D"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.23970"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(98)00120-7"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.103.5.1426"},{"key":"e_1_2_6_12_1","unstructured":"Haute Autorit\u00e9 de Sant\u00e9\u2014Asthme de l'enfant de moins de 36 mois: diagnostic prise en charge et traitement en dehors des \u00e9pisodes aigus [Internet]. 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