{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:35:12Z","timestamp":1788870912925,"version":"build-2803163510"},"reference-count":5,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,2,9]],"date-time":"2015-02-09T00:00:00Z","timestamp":1423440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"chILD-EU","award":["FP7, 305653"],"award-info":[{"award-number":["FP7, 305653"]}]},{"DOI":"10.13039\/501100003042","name":"Else Kr\u00f6ner-Fresenius-Stiftung","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100003042","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      Chronic interstitial lung diseases are rare in childhood and can present with a wide spectrum of histological abnormalities and radiological\u2010clinical phenotypes. A 17\u2010month\u2010old female infant with malnutrition, recurrent lower respiratory tract infections, and failure to thrive since 3 months of age was diagnosed as surfactant protein C deficiency. Diffuse, giant, and life\u2010threatening pneumatoceles developed during the course. They were treated with empiric drug treatment and oxygen support, and resolved rapidly. Substantial clinical and radiological improvement was observed 1 year after treatment initiation. Large\u2010giant pneumatoceles can develop in the course of surfactant protein C deficiency and may be associated with biopsy. They can resolve with medical treatment. If available, genetic testing should be attempted as a first step for diagnosis.\n                      <jats:bold>Pediatr Pulmonol. 2015; 50:E25\u2013E28.<\/jats:bold>\n                      \u00a9 2015 Wiley Periodicals, Inc.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.23162","type":"journal-article","created":{"date-parts":[[2015,2,12]],"date-time":"2015-02-12T12:59:22Z","timestamp":1423745962000},"source":"Crossref","is-referenced-by-count":5,"title":["Life\u2010threatening, giant pneumatoceles in the course of surfactant protein C deficiency"],"prefix":"10.1002","volume":"50","author":[{"given":"Tugba","family":"Sismanlar","sequence":"first","affiliation":[{"name":"Department of Pediatric Pulmonology Gazi University Hospital Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Tana","family":"Aslan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology Gazi University Hospital Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Griese","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology Hauner Children's Hospital Ludwig Maximilians University Member of the German Center for Lung Research (DZL) Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,9]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"244","article-title":"Interstitial lung disease in the course of the surfactant protein C deficiency coexisting with the primary humoral immunodeficiency\u2014a case report","volume":"78","author":"Szczawi\u0144ska\u2010Pop\u0142onyk A","year":"2010","journal-title":"Pneumonol Alergol Pol"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.00000104"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra022387"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22971"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200703-393OC"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.23162","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.23162","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.23162","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T02:38:47Z","timestamp":1696387127000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.23162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,9]]},"references-count":5,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1002\/ppul.23162"],"URL":"https:\/\/doi.org\/10.1002\/ppul.23162","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,9]]}}}