{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T02:59:25Z","timestamp":1781924365541,"version":"3.54.5"},"reference-count":76,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T00:00:00Z","timestamp":1451433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"none reported"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>Pediatric eosinophilic pneumonias (EPs) are characterized by a significant infiltration of the alveolar spaces and lung interstitium by eosinophils, with conservation of the lung structure. In developed countries, EPs constitute exceptional entities in pediatric care. Clinical symptoms may be transient (L\u00f6ffler syndrome), acute (&lt;1 month and mostly &lt;7 days), or chronic (&gt;1 month). Diagnosis relies on demonstration of alveolar eosinophilia on bronchoalveolar lavage, whether or not associated with blood eosinophilia. EPs are a heterogeneous group of disorders divided into: (i) secondary forms (seen mainly in parasitic infections, allergic bronchopulmonary aspergillosis, and drug reactions); and (ii) primary forms (eosinophilic granulomatosis with polyangiitis, hypereosinophilic syndrome, idiopathic chronic eosinophilic pneumonia, and idiopathic acute eosinophilic pneumonia). Despite their rarity, the etiological approach to EP must be well\u2010defined as some causes can be rapidly life\u2010threatening without initiation of the proper treatment. This approach (i) eliminates secondary forms, with comprehensive history taking and minimal biological assessment, (ii) is oriented in primary forms by the acute or chronic setting, and the existence of extrapulmonary symptoms. Treatment of primary forms has traditionally relied on corticosteroids, usually with a dramatic response. Specific treatments or the adjunction of corticosteroid\u2010sparing treatment or immunosuppressors are currently being evaluated in order to improve the prognosis and the side effects associated with corticosteroid treatment in a pediatric setting. <jats:bold>Pediatr Pulmonol. 2016;51:203\u2013216.<\/jats:bold> \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.23368","type":"journal-article","created":{"date-parts":[[2015,12,30]],"date-time":"2015-12-30T14:54:44Z","timestamp":1451487284000},"page":"203-216","source":"Crossref","is-referenced-by-count":36,"title":["Eosinophilic pneumonias in children: A review of the epidemiology, diagnosis, and treatment"],"prefix":"10.1002","volume":"51","author":[{"given":"Lisa","family":"Giovannini\u2010Chami","sequence":"first","affiliation":[{"name":"Department of Pediatric Pulmonology and Allergology H\u00f4pitaux p\u00e9diatriques de Nice CHU\u2010Lenval Nice France"},{"name":"Universit\u00e9 de Nice Sophia 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