{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:16:44Z","timestamp":1787498204844,"version":"build-2736575974"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T00:00:00Z","timestamp":1485734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"none reported"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Nontuberculous mycobacteria (NTM) have a particular affinity for patients with cystic fibrosis (CF). Recent studies suggest a possible relationship between acquiring NTM and the level of environmental water in a given area. We sought to determine if there is an association between household proximity to water and NTM in children with CF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>An IRB\u2010approved retrospective chart review was completed on 150 children with CF in Florida. Inclusion criteria required regular follow\u2010up, at least two acid\u2010fast bacilli cultures, and a consistent home address over a 3\u2010year period. The distance from each patient's home to the nearest body of water was measured using ArcMap\u00ae, a Geographic Information System, and the mean distance to water for NTM\u2010positive and NTM\u2010negative groups were compared. A stepwise backwards logistic regression was used to evaluate for predictors of NTM\u2010positivity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 150 CF patients, 65 met inclusion criteria and 21 (32.3%) tested positive for NTM. Comparison of the mean distance to water for NTM\u2010positive versus NTM\u2010negative groups revealed a cutoff of 500 meters. On the logistic regression, CF patients who lived within 500 meters of water were 9.4 times more likely to acquire NTM (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.013). Other significant predictors included a history of\n                      <jats:italic>Aspergillus fumigatus<\/jats:italic>\n                      (OR 7.9,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.011) and recent history of\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                      (OR 2.5,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.007).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      In the regions studied, children with CF who live closer to water are more likely to acquire nontuberculous mycobacteria. Future studies in other geographic areas are needed to determine if these results are generalizable.\n                      <jats:bold>Pediatr Pulmonol. 2017;52:324\u2013330.<\/jats:bold>\n                      \u00a9 2016 Wiley Periodicals, Inc.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.23646","type":"journal-article","created":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T11:18:32Z","timestamp":1485775112000},"page":"324-330","source":"Crossref","is-referenced-by-count":23,"title":["Household proximity to water and nontuberculous mycobacteria in children with cystic fibrosis"],"prefix":"10.1002","volume":"52","author":[{"given":"Jennifer M.","family":"Bouso","sequence":"first","affiliation":[{"name":"Pediatric Residency Program at Sacred Heart Hospital University of Florida Pensacola Florida"},{"name":"Department of Pediatric Pulmonology Nemours Children's Specialty Care Pensacola Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"Burns","sequence":"additional","affiliation":[{"name":"Pediatric Residency Program at Sacred Heart Hospital University of Florida Pensacola Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raid","family":"Amin","sequence":"additional","affiliation":[{"name":"Department of Mathematics and Statistics University of West Florida Pensacola Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Floyd R.","family":"Livingston","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology Nemours Children's Specialty Care Orlando Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Okan","family":"Elidemir","sequence":"additional","affiliation":[{"name":"Pediatric Residency Program at Sacred Heart Hospital University of Florida Pensacola Florida"},{"name":"Department of Pediatric Pulmonology Nemours Children's Specialty Care Pensacola Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2015.11.001"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-1984-0.00052-8"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens4020390"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2015.03.012"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1586\/17476348.2016.1162715"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1238912"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.39.5.369"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000714"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201405-0884OC"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2014.05.008"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200207-678OC"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20222"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2009.12.001"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200207-679OC"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1546751"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2012.01.006"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2016.03.002"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201307-1200OC"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2012.06.009"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2015.02.006"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1333574"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00058604"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21106"},{"key":"e_1_2_6_25_1","unstructured":"JenniferA KennethNO PrevotsDR.Predictors of Prolonged Nontuberculous Mycobacterial Infections in Patients with Cystic Fibrosis. 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