{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:31:00Z","timestamp":1783776660293,"version":"3.55.0"},"reference-count":154,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T00:00:00Z","timestamp":1482883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"none reported"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:label\/><jats:p>Obstructive sleep\u2010disordered breathing (SDB) can result in cardiovascular and neurocognitive morbidity as well as adversely affect behavior, growth, quality of life, and nocturnal continence. This article summarizes the latest evidence regarding the morbidity related to obstructive SDB, commenting on the impact of severity of obstruction, that is, the difference in effects seen of moderate to severe obstructive sleep apnea syndrome (OSAS) compared to those of mild OSAS or primary snoring. The impact of therapy is discussed, focusing on which children are likely to benefit from treatment interventions; namely those with moderate or severe OSAS irrespective of the presence of morbidity, children with mild OSAS with associated morbidity or predictors of SDB persistence such as obesity, and children with complex conditions accompanied by upper airway obstruction like craniosynostosis and Prader\u2013Willi syndrome. The co\u2010existing conditions which may improve when treatment for obstructive SDB is offered are reviewed, while the clinical parameters associated with spontaneous improvement or resolution of obstructive SDB are discussed. The intention being to enable clinicians to make informed decisions on who should be treated, when and why. <jats:bold>Pediatr Pulmonol. 2017;52:399\u2013412.<\/jats:bold> \u00a9 2016 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.23658","type":"journal-article","created":{"date-parts":[[2016,12,28]],"date-time":"2016-12-28T15:57:29Z","timestamp":1482940649000},"page":"399-412","source":"Crossref","is-referenced-by-count":39,"title":["When and why to treat the child who snores?"],"prefix":"10.1002","volume":"52","author":[{"given":"Hui\u2010Leng","family":"Tan","sequence":"first","affiliation":[{"name":"Department of Pediatric Respiratory Medicine Royal Brompton Hospital Sydney St. London SW3 6NP United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Luz","family":"Alonso Alvarez","sequence":"additional","affiliation":[{"name":"Multidisciplinary Sleep Unit, Pulmonology, University Hospital of Burgos and CIBER of Respiratory Diseases (CIBERES) Burgos Foundation for Health Research Burgos Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Tsaoussoglou","sequence":"additional","affiliation":[{"name":"Pediatric Pulmonology Unit, First Department of Pediatrics National and Kapodistrian University of Athens School of Medicine and Aghia Sophia Children's Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Otolaryngology and Head and Neck Surgery, Botucatu Medical School S\u00e3o Paulo State University\u2010UNESP Botucatu, S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Athanasios G.","family":"Kaditis","sequence":"additional","affiliation":[{"name":"Pediatric Pulmonology Unit, First Department of Pediatrics National and Kapodistrian University of Athens School of Medicine and Aghia Sophia Children's Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,28]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00385-2015"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2013.12.003"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2008.141192"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23323"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215881"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-0620"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-3099"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01771-2015"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.01.033"},{"key":"e_1_2_15_11_1","article-title":"How do we recognize the child with OSAS","author":"Joosten K","year":"2016","journal-title":"Pediatr Pulmonol"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0069710"},{"key":"e_1_2_15_13_1","first-page":"797s","article-title":"Urine uric acid excretion in obese and nonobese children with obstructive sleep\u2010disordered breathing","volume":"32","author":"Kaditis A","year":"2008","journal-title":"Eur Respir J"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200808-1324OC"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3800"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.03.024"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2015.37"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/32.10.1265"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1113\/EP085092"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1990.69.6.2143"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.74.6.2969"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00198.2015"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/20.2.151"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2009.11.012"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20916"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.07.010"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2606"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2010.09.015"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.01.015"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.09.011"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.2108"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.93.1.119"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950040304"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2009.05.019"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/28.6.747"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.5.1377"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2049"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20811"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2011.01.014"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-1555"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.11.044"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.07.021"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.04.011"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.696823"},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.4976"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.16303"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.1.8111575"},{"key":"e_1_2_15_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2015.67"},{"key":"e_1_2_15_49_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2026"},{"key":"e_1_2_15_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2010.154"},{"key":"e_1_2_15_51_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2805"},{"key":"e_1_2_15_52_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1261"},{"key":"e_1_2_15_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2014.137"},{"key":"e_1_2_15_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2005.11.012"},{"key":"e_1_2_15_55_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-0591"},{"key":"e_1_2_15_56_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2004-0730"},{"key":"e_1_2_15_57_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0435"},{"key":"e_1_2_15_58_1","first-page":"495","article-title":"Subjective sleepiness and polysomnographic correlates in children scheduled for adenotonsillectomy vs other surgical care","volume":"29","author":"Chervin RD","year":"2006","journal-title":"Sleep"},{"key":"e_1_2_15_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/34.4.503"},{"key":"e_1_2_15_60_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.3.693"},{"key":"e_1_2_15_61_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-0228"},{"key":"e_1_2_15_62_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1837"},{"key":"e_1_2_15_63_1","first-page":"894","article-title":"Sleep in children with attention\u2010deficit\/hyperactivity disorder: meta\u2010analysis of subjective and objective studies","volume":"48","author":"Cortese S","year":"2009","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"e_1_2_15_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2006.03.004"},{"key":"e_1_2_15_65_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1819.2001.00808.x"},{"key":"e_1_2_15_66_1","first-page":"517","article-title":"Risk of behavioral and adaptive functioning difficulties in youth with previous and current sleep disordered breathing","volume":"36","author":"Perfect MM","year":"2013","journal-title":"Sleep"},{"key":"e_1_2_15_67_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27491"},{"key":"e_1_2_15_68_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.3.616"},{"key":"e_1_2_15_69_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-4458"},{"key":"e_1_2_15_70_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00082904"},{"key":"e_1_2_15_71_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0139142"},{"key":"e_1_2_15_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03045026"},{"key":"e_1_2_15_73_1","doi-asserted-by":"publisher","DOI":"10.1076\/1380-3395(200010)22:5;1-9;FT554"},{"key":"e_1_2_15_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-011-0480-6"},{"key":"e_1_2_15_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2010.06.019"},{"key":"e_1_2_15_76_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201510-2099OC"},{"key":"e_1_2_15_77_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsj035"},{"key":"e_1_2_15_78_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-1402"},{"key":"e_1_2_15_79_1","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2015.00584"},{"key":"e_1_2_15_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2005.11.035"},{"key":"e_1_2_15_81_1","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318093edd7"},{"key":"e_1_2_15_82_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.MLG.0000181516.65577.94"},{"key":"e_1_2_15_83_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.10.974"},{"key":"e_1_2_15_84_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.74"},{"key":"e_1_2_15_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2007.11.003"},{"key":"e_1_2_15_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2015.03.021"},{"key":"e_1_2_15_87_1","doi-asserted-by":"publisher","DOI":"10.1159\/000108366"},{"key":"e_1_2_15_88_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-0620"},{"key":"e_1_2_15_89_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.4318"},{"key":"e_1_2_15_90_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.120220"},{"key":"e_1_2_15_91_1","first-page":"1736","article-title":"Montelukast for children with obstructive sleep apnea: results of a double\u2010blind, randomized, placebo\u2010controlled trial","volume":"13","author":"Kheirandish\u2010Gozal L","year":"2016","journal-title":"Ann Am Thorac Soc"},{"key":"e_1_2_15_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2007.08.002"},{"key":"e_1_2_15_93_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-011-2410-0"},{"key":"e_1_2_15_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007810.pub2"},{"key":"e_1_2_15_95_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0b013e32835b11a1"},{"key":"e_1_2_15_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2014.01.005"},{"key":"e_1_2_15_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21497"},{"key":"e_1_2_15_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.10.008"},{"key":"e_1_2_15_99_1","first-page":"83","article-title":"Sleep\u2010disordered breathing in children with asthma: a systematic review on the impact of treatment","volume":"9","author":"Sanchez T","year":"2016","journal-title":"J Asthma Allergy"},{"key":"e_1_2_15_100_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-015-1291-y"},{"key":"e_1_2_15_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2008.152"},{"key":"e_1_2_15_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spen.2015.04.006"},{"key":"e_1_2_15_103_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200703-375OC"},{"key":"e_1_2_15_104_1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.52010\/ijom.2010.36.1.3","article-title":"Speech\u2010language pathology findings in patients with mouth breathing: multidisciplinary diagnosis according to etiology","volume":"36","author":"Junqueira P","year":"2010","journal-title":"Int J Orofacial Myol"},{"key":"e_1_2_15_105_1","doi-asserted-by":"publisher","DOI":"10.1080\/14015430903066937"},{"key":"e_1_2_15_106_1","doi-asserted-by":"publisher","DOI":"10.1179\/2151090314Y.0000000029"},{"key":"e_1_2_15_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2007.03.011"},{"key":"e_1_2_15_108_1","doi-asserted-by":"crossref","first-page":"247","DOI":"10.5664\/jcsm.26338","article-title":"Clinical screening of school children for polysomnography to detect sleep\u2010disordered breathing\u2014the Tucson children's assessment of sleep apnea study (TuCASA)","volume":"1","author":"Goodwin JL","year":"2005","journal-title":"J Clin Sleep Med"},{"key":"e_1_2_15_109_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.153.2.8564147"},{"key":"e_1_2_15_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2014.06.009"},{"key":"e_1_2_15_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2009.03.041"},{"key":"e_1_2_15_112_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.123.5.1561"},{"key":"e_1_2_15_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.05.038"},{"key":"e_1_2_15_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2015.10.002"},{"key":"e_1_2_15_115_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-1224"},{"key":"e_1_2_15_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.05.008"},{"key":"e_1_2_15_117_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2015.2354"},{"key":"e_1_2_15_118_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.08.009"},{"key":"e_1_2_15_119_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1671"},{"key":"e_1_2_15_120_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001665-200407000-00026"},{"key":"e_1_2_15_121_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.98.11040866"},{"key":"e_1_2_15_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2009.10.029"},{"key":"e_1_2_15_123_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2012-302745"},{"key":"e_1_2_15_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2015.05.010"},{"key":"e_1_2_15_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(86)80008-8"},{"key":"e_1_2_15_126_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2615"},{"key":"e_1_2_15_127_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.2004.00870.x"},{"key":"e_1_2_15_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-8966(02)00219-5"},{"key":"e_1_2_15_129_1","doi-asserted-by":"publisher","DOI":"10.1053\/rmed.1999.0730"},{"key":"e_1_2_15_130_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.49.2.157"},{"key":"e_1_2_15_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.2005.00691.x"},{"key":"e_1_2_15_132_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27941"},{"key":"e_1_2_15_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/0960-8966(96)00357-4"},{"key":"e_1_2_15_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ridd.2007.01.003"},{"key":"e_1_2_15_135_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2013.02.009"},{"key":"e_1_2_15_136_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.35441"},{"key":"e_1_2_15_137_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.79.2.99"},{"key":"e_1_2_15_138_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/831569"},{"key":"e_1_2_15_139_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2005.085324"},{"key":"e_1_2_15_140_1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.5664\/jcsm.2592","article-title":"Sleep disordered breathing in children and adolescents with Chiari malformation type I","volume":"9","author":"Losurdo A","year":"2013","journal-title":"J Clin Sleep Med"},{"key":"e_1_2_15_141_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.95.5.1064"},{"key":"e_1_2_15_142_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.5554"},{"key":"e_1_2_15_143_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12376"},{"key":"e_1_2_15_144_1","doi-asserted-by":"publisher","DOI":"10.4250\/jcu.2015.23.2.72"},{"key":"e_1_2_15_145_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-014-0944-6"},{"key":"e_1_2_15_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2014.03.021"},{"key":"e_1_2_15_147_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33902"},{"key":"e_1_2_15_148_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23177"},{"key":"e_1_2_15_149_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.12109"},{"key":"e_1_2_15_150_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3616"},{"key":"e_1_2_15_151_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.30777"},{"key":"e_1_2_15_152_1","doi-asserted-by":"publisher","DOI":"10.1159\/000097928"},{"key":"e_1_2_15_153_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2013-303760"},{"key":"e_1_2_15_154_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2007.126334"},{"key":"e_1_2_15_155_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2008-0649"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.23658","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.23658","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T13:24:52Z","timestamp":1696512292000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.23658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,28]]},"references-count":154,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1002\/ppul.23658"],"URL":"https:\/\/doi.org\/10.1002\/ppul.23658","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,28]]}}}