{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T02:10:47Z","timestamp":1789179047091,"version":"build-2803163510"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T00:00:00Z","timestamp":1488844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>The aim of this study was to investigate whether functional respiratory imaging (FRI) or clinical examination could predict treatment outcome for obstructive sleep apnea (OSA) in normal\u2010weight, non\u2010syndromic children.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Normal weight children diagnosed with OSA by polysomnography were prospectively included. All children got a thorough evaluation and an ultra\u2010low dose computed tomography scan of the upper airway (UA). A 3\u2010D reconstruction was built combined with computational fluid dynamics for FRI. Decisions on the need and type of surgery were based upon findings during drug\u2010induced sleep endoscopy. A second polysomnography was performed 3\u201012 months after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Ninety\u2010one children were included: 62 boys, 5.0\u2009\u00b1\u20092.7 years, and BMI z\u2010score of \u22120.1\u2009\u00b1\u20091.2. Children with more severe OSA had a smaller volume of the overlap region between the adenoids and tonsils. Nineteen out of 60 patients had persistent OSA (oAHI &gt;2\/h). A lower conductance in the UA and a higher tonsil score predicted successful treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>A less constricted airway, as characterized by both FRI and a lower tonsil score, was associated with a less favorable response to (adeno) tonsillectomy. Further studies after treatment using FRI and DISE are warranted to further characterize the UA of these subjects.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.23684","type":"journal-article","created":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T15:12:44Z","timestamp":1488899564000},"page":"799-805","source":"Crossref","is-referenced-by-count":11,"title":["Predicting the effect of treatment in paediatric OSA by clinical examination and functional respiratory imaging"],"prefix":"10.1002","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5146-1323","authenticated-orcid":false,"given":"Monique","family":"Slaats","sequence":"first","affiliation":[{"name":"Department of Paediatrics Antwerp University Hospital Edegem Belgium"},{"name":"Laboratory of Experimental Medicine and Paediatrics (LEMP) University of Antwerp Universiteitsplein 1 Antwerp 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