{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:47:57Z","timestamp":1760550477888,"version":"3.37.3"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T00:00:00Z","timestamp":1517184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The Science and Technology Key Project of Jinhua City","award":["20163011"],"award-info":[{"award-number":["20163011"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study was designed to establish a porcine model of reversible obstruction of endobronchial foreign body (FB) and to assess the natural pulmonary reexpansion process using radiology and histopathology after removal of the bronchial FB.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A metal stent was placed in the right lower lobe bronchial lumen of 15 pigs by bronchoscopy and removed after 2 weeks of stent retention. Animals were divided into two groups (group I and II), based on when they were sacrificed (week 2 or week 4) after stent removal. Pigs underwent computerized tomography scan to document pulmonary radiological changes. The lungs were harvested for electron microscopy examination, and the expression of pulmonary surfactant\u2010associated protein A (SPA) was determined by immunohistochemistry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirteen (86.7%) animals successfully responded to the intervention. Atelectasis was formed by stent implantation within 2 weeks. The ratio of the residual atelectasis area was smaller in group II compared to that in group I (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). The histological manifestations of experimental lungs were significantly improved in group II. Moreover, the expression of SPA in group II was higher compared to that in group I (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We have established a model of reversible bronchial FB obstruction in pigs that is both feasible and appropriate for evaluating the long\u2010term process of pulmonary reexpansion after removal of FB. Bronchial metal FB retention for a period of 2 weeks could form atelectasis, and a natural pulmonary recovery process related to atelectasis takes approximately 4 weeks after removal of metal FB.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.23947","type":"journal-article","created":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T21:50:57Z","timestamp":1517262657000},"page":"278-283","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of pulmonary reexpansion in a porcine model of bronchial foreign body"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1749-1200","authenticated-orcid":false,"given":"Saibin","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Jinling Clinical Medical College of Nanjing Medical University Nanjing China"},{"name":"Department of Respiratory Medicine Jinhua Municipal Central Hospital Jinhua Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junwei","family":"Tu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Jinhua Municipal Central Hospital Jinhua Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine Jinling Clinical Medical College of Nanjing Medical University Nanjing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,29]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_7_2_1","DOI":"10.1016\/S0022-3468(84)80097-4"},{"doi-asserted-by":"publisher","key":"e_1_2_7_3_1","DOI":"10.1016\/j.ijporl.2012.02.004"},{"doi-asserted-by":"publisher","key":"e_1_2_7_4_1","DOI":"10.3906\/sag-1504-86"},{"doi-asserted-by":"publisher","key":"e_1_2_7_5_1","DOI":"10.1002\/ppul.10116"},{"key":"e_1_2_7_6_1","doi-asserted-by":"crossref","first-page":"121","DOI":"10.4187\/respcare.02352","article-title":"Experimental model of atelectasis in newborn piglets","volume":"59","author":"Comaru T","year":"2014","journal-title":"Respir Care"},{"key":"e_1_2_7_7_1","first-page":"896","article-title":"Effects of expiratory rib cage compression combined with endotracheal suctioning on gas exchange in mechanically ventilated rabbits with induced atelectasis","volume":"49","author":"Unoki T","year":"2004","journal-title":"Respir Care"},{"key":"e_1_2_7_8_1","first-page":"550","article-title":"Second place\u2010resident clinical science award 1990. 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