{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T20:05:23Z","timestamp":1790193923142,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T00:00:00Z","timestamp":1524441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Continuous positive airway pressure (CPAP) delivered via binasal prongs has been the cornerstone of respiratory management in preterm infants. Though effective, the use of binasal prongs is associated with nasal trauma, and CPAP failure. To overcome these issues, nasal masks are increasingly used to deliver CPAP in preterm infants. The aim was to conduct a systematic review of randomized controlled trials (RCTs) comparing nasal mask versus binasal prongs to deliver CPAP in preterm infants. Medline, Embase, Cochrane Central Register of Controlled Trials, Cumulative Index of Nursing, and Allied Health Literature, and E\u2010abstracts from the Pediatric Academic Society meetings were searched in May 2017. All RCTs comparing nasal mask versus binasal prongs for delivering CPAP in preterm infants were included. Primary outcome was CPAP failure (need for mechanical ventilation within 72\u2009h of initiating CPAP). Secondary outcomes included duration of CPAP, moderate to severe nasal trauma, any nasal trauma, pneumothorax, severe IVH, bronchopulmonary dysplasia at 36 weeks postmenstrual age, and mortality. Five RCTs with low risk of bias were included. Nasal mask significantly decreased the risk of CPAP failure (4 RCTs [<jats:italic>N<\/jats:italic>\u2009=\u2009459]; relative risk [RR]: 0.63; 95% confidence interval [CI]: 0.45\u20100.88; <jats:italic>P<\/jats:italic>=.007; I2\u2009=\u20090%, NNT: 9), and the incidence of moderate to severe nasal trauma (3 RCTs [<jats:italic>N<\/jats:italic>\u2009=\u2009275], RR: 0.41; 95%CI, 0.24\u20100.72; <jats:italic>P<\/jats:italic>\u2009=\u20090.002; I2\u2009=\u200974%, NNT: 6). Other outcomes did not differ significantly between the groups. Compared to binasal prongs, nasal mask may provide a safe and effective alternative by minimizing the risk of CPAP failure in preterm infants needing CPAP support.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.24014","type":"journal-article","created":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T05:46:29Z","timestamp":1524548789000},"page":"987-992","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":50,"title":["Effectiveness and safety of nasal mask versus binasal prongs for providing continuous positive airway pressure in preterm infants\u2014A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9772-3237","authenticated-orcid":false,"given":"Bonny","family":"Jasani","sequence":"first","affiliation":[{"name":"Division of Neonatology Hospital for Sick Children Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu","family":"Ismail","sequence":"additional","affiliation":[{"name":"Division of Neonatology Hospital for Sick Children Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shripada","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Neonatal Paediatrics King Edward Memorial Hospital for Women Perth Western Australia"},{"name":"Centre for Neonatal Research and Education University of Western Australia Perth Western Australia"},{"name":"Department of Neonatal Paediatrics Princess Margaret Hospital for Children Perth Western Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Patole","sequence":"additional","affiliation":[{"name":"Department of Neonatal Paediatrics King Edward Memorial Hospital for Women Perth Western Australia"},{"name":"Centre for Neonatal Research and Education University of Western Australia Perth Western Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,4,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072788"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0911783"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2131"},{"key":"e_1_2_6_5_1","first-page":"CD002977","article-title":"Devices and pressure sources for administration of nasal continuous positive airway pressure (NCPAP) in preterm neonates","volume":"1","author":"De Paoli AG","year":"2008","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/fn.87.1.F42"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/fn.75.3.F209"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/0104-1169.3451.2486"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0080-623420130000600005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.069351"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-3548"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-015-0769-9"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000443263"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-017-2851-x"},{"key":"e_1_2_6_15_1","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions","author":"Higgins J","year":"2011"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e3181fe7825"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2012.01.012"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apnr.2014.05.005"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/fn.75.3.F209"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.179416"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7210865"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2006.01.015"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-004-2267-8"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2009.179416"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.24014","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.24014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,17]],"date-time":"2023-09-17T21:16:10Z","timestamp":1694985370000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.24014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,23]]},"references-count":23,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1002\/ppul.24014"],"URL":"https:\/\/doi.org\/10.1002\/ppul.24014","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,23]]},"assertion":[{"value":"2017-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-02-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}