{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T09:31:07Z","timestamp":1774085467317,"version":"3.50.1"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Current guidelines recommend initiating continuous positive airway pressure (CPAP) in children during an overnight in\u2010hospital titration study. Due to a shortage of hospital beds and economic constraints, we started a program for outpatient initiation of CPAP in selected children with obstructive sleep apnea (OSA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Objective CPAP compliance and efficacy were evaluated in consecutive children enrolled in an outpatient CPAP program when they fulfilled the following criteria: persistent OSA, age &gt;6 months, stable condition, family living in the Parisian area and agreeing with a regular follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010one children, median (range) age 8.9 years (0.8\u201017.5), were included in the program. The most common diagnosis were Down syndrome (<jats:italic>n<\/jats:italic>\u2009=\u20097), achondroplasia (<jats:italic>n<\/jats:italic>\u2009=\u20093), and obesity (<jats:italic>n<\/jats:italic>\u2009=\u20093). Median baseline obstructive apnea\u2010hypopnea index (OAHI) was 12.5 events\/h (5\u2010100). Median duration of follow\u2010up was 12.3 months (2.2\u201025.2). Four subjects (three adolescents with Down syndrome) were not compliant at 2\u2010month follow\u2010up with a compliance\u2009&lt;4\u2009h\/night. In the other 27 subjects, median compliance was 08:21\u2009h:min\/night (05:45\u201012:20), with a median number of night use per month of 25 (18\u201030). CPAP efficacy at the end of follow\u2010up was excellent in the compliant subjects with a median AHI of two events\/h (0\u20104) and normal gas exchange with CPAP therapy. Three subjects were successfully weaned from CPAP treatment during the study period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Initiating CPAP in an outpatient setting in children is feasible and effective in selected subjects. A high rate of compliance can be achieved as well as a correction of OSA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.24138","type":"journal-article","created":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T14:01:07Z","timestamp":1533304867000},"page":"1422-1428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Outpatient initiation of long\u2010term continuous positive airway pressure in children"],"prefix":"10.1002","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2117-0781","authenticated-orcid":false,"given":"Alessandro","family":"Amaddeo","sequence":"first","affiliation":[{"name":"Pediatric Noninvasive Ventilation and Sleep Unit AP\u2010HP, H\u00f4pital Necker\u2010Enfants Malades Paris France"},{"name":"Paris Descartes University Paris France"},{"name":"INSERM U 955, Team 13 Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annick","family":"Frapin","sequence":"additional","affiliation":[{"name":"Pediatric Noninvasive Ventilation and Sleep Unit AP\u2010HP, H\u00f4pital Necker\u2010Enfants Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samira","family":"Touil","sequence":"additional","affiliation":[{"name":"Pediatric Noninvasive Ventilation and Sleep Unit AP\u2010HP, H\u00f4pital Necker\u2010Enfants Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4163-5021","authenticated-orcid":false,"given":"Sonia","family":"Khirani","sequence":"additional","affiliation":[{"name":"Pediatric Noninvasive Ventilation and Sleep Unit AP\u2010HP, H\u00f4pital Necker\u2010Enfants Malades Paris France"},{"name":"ASV Sant\u00e9 Gennevilliers France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucie","family":"Griffon","sequence":"additional","affiliation":[{"name":"Pediatric Noninvasive Ventilation and Sleep Unit AP\u2010HP, H\u00f4pital Necker\u2010Enfants Malades Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6092-2662","authenticated-orcid":false,"given":"Brigitte","family":"Fauroux","sequence":"additional","affiliation":[{"name":"Pediatric Noninvasive Ventilation and Sleep Unit AP\u2010HP, H\u00f4pital Necker\u2010Enfants Malades Paris France"},{"name":"Paris Descartes University Paris France"},{"name":"INSERM U 955, Team 13 Cr\u00e9teil France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3796"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1672"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23416"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2012.06.001"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-010-0479-4"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rppneu.2013.08.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2009.01681.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-0856"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27133"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.04.013"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.6590"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/zsw051"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-016-1400-6"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2008.07.019"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2014.07.008"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.87.5.438"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.122.5.1695"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2013.06.020"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.07.030"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000330598"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2017.05.019"},{"key":"e_1_2_8_23_1","unstructured":"1061109_TrilogyWrkshpUS_Booklet.pdf. 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