{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:55:04Z","timestamp":1787165704056,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2019,7,25]],"date-time":"2019-07-25T00:00:00Z","timestamp":1564012800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>A variety of inhaled antigens have been implicated to cause hypersensitivity pneumonitis (HP). We observed that children force\u2010fed with lentil\u2010based weaning food had persistent respiratory symptoms and radiology similar to HP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To describe the clinical features of lentil HP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective review of records of children with lentil HP attending Pediatric Chest Clinic at a tertiary care hospital in North India from 2008\u20102018. We included case records with elevated immunoglobulin G (IgG) specific for lentil antigen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements and Main Results<\/jats:title>\n                    <jats:p>\n                      Nine children (seven boys) were identified with median (IQR) age of onset of symptoms and diagnosis at 9 (6, 12) and 11 (10, 16) months, respectively. Chronic cough (100%), shortness of breath (89%), fever (78%), vomiting (56%), and wheezing (33%) were common symptoms. Fine crackles were heard in 33% of children, none had clubbing. CT scans showed nodular opacities and consolidation in 78% and 67% children, respectively. Bronchoalveolar lavage showed increased neutrophils and lymphocytes (67% and 33%, respectively). All children showed rapid remission with systemic steroids (prednisolone), starting at a median dose of 1 (1, 1.1)\u2009mg\u2009kg\n                      <jats:sup>\u22121<\/jats:sup>\n                      \u2009day\n                      <jats:sup>\u22121<\/jats:sup>\n                      . One child had a clinical relapse which was treated with oral steroids again. IgG specific to lentil antigens was elevated in children with lentil HP (21\u2010&gt;200\u2009mgA\/L) compared with children with other chronic respiratory illnesses (n\u2009=\u20097, &lt;2\u201011.4\u2009mgA\/L).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Lentil aspiration is an important cause of HP in infants of weaning age with force\u2010feeding practices. Further studies are needed to identify aspirated antigens which cause HP in aspiration prone children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.24463","type":"journal-article","created":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T01:34:51Z","timestamp":1564104891000},"page":"1781-1786","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Lentil aspiration leading to likely hypersensitivity pneumonitis"],"prefix":"10.1002","volume":"54","author":[{"given":"Nitin","family":"Dhochak","sequence":"first","affiliation":[{"name":"Department of Pediatrics All India Institute of Medical Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3642-246X","authenticated-orcid":false,"given":"Kana R.","family":"Jat","sequence":"additional","affiliation":[{"name":"Department of Pediatrics All India Institute of Medical Sciences  New Delhi 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