{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:15:30Z","timestamp":1740104130628,"version":"3.37.3"},"reference-count":42,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T00:00:00Z","timestamp":1578355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Ontario Lung Association"},{"name":"SickKids Foundation"},{"name":"Don and Debbie Morrison"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The test for respiratory and asthma control in kids (TRACK score) is a standardized questionnaire tool validated to identify poor symptom control in children with stable preschool wheeze. This study determined if TRACK score measured within 5 days of an Emergency Department (ED) visit for acute wheezing predicts a subsequent wheezing exacerbation requiring an ED visit and\/or treatment with systemic corticosteroids within 3 months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center prospective cohort study of children aged 36 to 71 months who presented to the ED with an acute episode of wheezing and had TRACK score measured at a clinic visit within 5 days of the index ED encounter, focused on information about symptoms occurring before the onset of the current acute episode. The outcomes were the independent association of a repeat wheezing exacerbation with the overall TRACK score (primary) and with mutually uncorrelated TRACK items (secondary), adjusted for sex and atopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We enrolled 102 children; median age 52.3 (44.1, 59.9) months, 59% males. Of these, 33 (32.4%) had further wheezing exacerbations. For each 10 unit decrease in TRACK, the odds of a future exacerbation was 1.38 (95% CI, 1.10\u20101.75); male sex demonstrated OR, 5.13 (1.84\u201014.33). A model that included TRACK items reflecting more than equal to 1 awakenings for wheezing in the past 4 weeks, receipt of more than equal to 2 courses of corticosteroids in the last year and male sex was predictive of wheezing exacerbations: OR, 6.43 (2.18\u201019.00).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In preschoolers with acute wheezing episodes in the ED, we have identified the TRACK score components which, together with male sex, can be used to identify children at risk of future exacerbations requiring referral for specialized care. These results need to be confirmed and validated in other populations enrolled at multiple sites before they can be implemented in practice.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.24601","type":"journal-article","created":{"date-parts":[[2020,1,7]],"date-time":"2020-01-07T12:18:30Z","timestamp":1578399510000},"page":"338-345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Test for respiratory and asthma control in preschool kids in the emergency department as a predictor of wheezing exacerbations"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4431-7061","authenticated-orcid":false,"given":"Maya","family":"Harel\u2010Sterling","sequence":"first","affiliation":[{"name":"Division of Paediatric Emergency Medicine, Department of Paediatrics, and Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruixue","family":"Dai","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, and Department of Physiology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9968-6601","authenticated-orcid":false,"given":"Theo J.","family":"Moraes","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, and Department of Physiology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathy","family":"Boutis","sequence":"additional","affiliation":[{"name":"Division of Paediatric Emergency Medicine, Department of Paediatrics, and Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Eiwegger","sequence":"additional","affiliation":[{"name":"Division of Immunology &amp; Allergy, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute The Hospital for Sick Children, and University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Indra","family":"Narang","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, and Department of Physiology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Lepine","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, and Department of Physiology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"May Grace","family":"Brydges","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, and Department of Physiology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aimee","family":"Dubeau","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, and Department of Physiology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0394-1933","authenticated-orcid":false,"given":"Padmaja","family":"Subbarao","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine, Department of Paediatrics, and Program in Translational Medicine, SickKids Research Institute, The Hospital for Sick Children, and Department of Physiology University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Schuh","sequence":"additional","affiliation":[{"name":"Division of Paediatric Emergency Medicine, Department of Paediatrics, and Child Health Evaluative Sciences, SickKids Research Institute, The Hospital for Sick Children University of Toronto  Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,1,7]]},"reference":[{"issue":"2","key":"e_1_2_8_2_1","first-page":"45","article-title":"Changes in the prevalence of asthma among Canadian children","volume":"19","author":"Garner R","year":"2008","journal-title":"Health Rep"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0168"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0371"},{"issue":"20","key":"e_1_2_8_5_1","first-page":"1535","article-title":"From the centers for disease control and prevention","volume":"275","author":"Asthma mortality and hospitalization among children and young adults\u2013united states, 1980\u20101993","year":"1996","journal-title":"JAMA"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2000.109426"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.129.4.909"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199501193320301"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200504-525OC"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.06.011"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.04.025"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.05.022"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200702-212OC"},{"key":"e_1_2_8_14_1","unstructured":"AsthmaGIf.2018.Global strategy for asthma management and prevention.Ginasthma.Org. Accessed on December 17 2018."},{"issue":"5","key":"e_1_2_8_15_1","doi-asserted-by":"crossref","first-page":"S94","DOI":"10.1016\/j.jaci.2007.09.029","article-title":"Expert panel report 3 (EPR\u20103): guidelines for the diagnosis and management of asthma\u2010summary report 2007","volume":"120","author":"Expert panel report 3 (epr\u20103): Guidelines for the diagnosis and management of asthma\u2010summary report 2007","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.12.980"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016-3438"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.08.010"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.01.058"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-1465"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/pch\/20.7.353"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.08.024"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2009.02105.x"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2016-209429"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.4.9912111"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-4496"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201402-084OC"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/03610919708813397"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/80.1.27"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-3462-1"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/bimj.201700067"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.09.008"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00117509"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.05.031"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2012.05.015"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.07.018"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-006-6067-1"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.08.021"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.09.006"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.56.8.589"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2012.08.004"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-1055"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.82.4.327"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fppul.24601","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.24601","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ppul.24601","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.24601","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T22:18:12Z","timestamp":1694038692000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.24601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,7]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["10.1002\/ppul.24601"],"URL":"https:\/\/doi.org\/10.1002\/ppul.24601","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"type":"print","value":"8755-6863"},{"type":"electronic","value":"1099-0496"}],"subject":[],"published":{"date-parts":[[2020,1,7]]},"assertion":[{"value":"2019-06-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-07","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}