{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T02:33:00Z","timestamp":1781663580671,"version":"3.54.5"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T00:00:00Z","timestamp":1581465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Asthma and postinfectious bronchiolitis obliterans (PIBO) have similar clinical findings, and PIBO may be misdiagnosed with asthma. This study aimed to determine the clinical features of PIBO in children and the causes of delay in its diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively evaluated all patients diagnosed with PIBO in four pediatric pulmonology centers between 2007 and 2018. In total, 64 PIBO patients were retrospectively reviewed. We compared the clinical and laboratory differences between PIBO patients who had initially been misdiagnosed with asthma and correctly diagnosed with PIBO.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 64 patients, 22 (34.4%) had initially been misdiagnosed with asthma. Adenovirus was the most common infectious agent in children. The age upon diagnosis was older, and the symptom duration was significantly longer in patients misdiagnosed with asthma (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.05). There were no statistical differences in terms of sex, history of prematurity, duration of hospitalization, treatment, history of oxygen or mechanical ventilation support, pulmonary function test (PFT) results and asthma\u2010predisposing findings between the two groups (<jats:italic>P<\/jats:italic>\u2009&gt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients with PIBO who had initially been misdiagnosed with asthma were correctly diagnosed at older ages and had longer symptom duration. Asthma may mask PIBO diagnosis by the similarity of symptoms and the clinical response to inhaled \u03b22\u2010agonist or steroid treatment. PFTs may not help clinicians because of the age of children. The delay in the diagnosis of PIBO is probably attributable to the fact that some clinicians fail to include PIBO in the differential diagnosis when there is no clinical response to asthma medication.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.24690","type":"journal-article","created":{"date-parts":[[2020,2,12]],"date-time":"2020-02-12T14:41:37Z","timestamp":1581518497000},"page":"1007-1011","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Postinfectious bronchiolitis obliterans masked by misdiagnosis as asthma"],"prefix":"10.1002","volume":"55","author":[{"given":"Zeynep R.","family":"Onay","sequence":"first","affiliation":[{"name":"Department of Pediatric Pulmonology Faculty of Medicine Gazi University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tugba","family":"Ramasli Gursoy","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology Faculty of Medicine Gazi University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5360-8517","authenticated-orcid":false,"given":"Ayse T.","family":"Aslan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology Faculty of Medicine Gazi University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7284-4999","authenticated-orcid":false,"given":"Tugba","family":"Sismanlar Eyuboglu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology Faculty of Medicine Gazi University  Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Busra S.","family":"Kibar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Meram Medicine Faculty Necmettin Erbakan University  Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevgi","family":"Pekcan","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Meram Medicine Faculty Necmettin Erbakan University  Konya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melih","family":"Hangul","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Faculty of Medicine Erciyes University  Kayseri Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3003-918X","authenticated-orcid":false,"given":"Mehmet","family":"Kose","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology, Faculty of Medicine Erciyes University  Kayseri Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isil I.","family":"Budakoglu","sequence":"additional","affiliation":[{"name":"Department of Medical Education, Faculty of Medicine Gazi University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bahar","family":"Gokturk","sequence":"additional","affiliation":[{"name":"Department of Pediatric Allergy and Immunology, Faculty of Medicine Baskent University Konya 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