{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:15:27Z","timestamp":1740104127394,"version":"3.37.3"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Intrapulmonary percussive ventilation (IPV) is an airway clearance technique used at any age to facilitate the removal of secretions from the respiratory tract. The effect of IPV on gastroesophageal reflux(GER) is not well documented. This study aimed to determine the influence of IPV on GER in infants.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>During a 24\u2010hour multichannel intraluminal impedance\u2010pH monitoring (MII\u2010pH), infants in the intervention group received a20 minutes session of IPV in upright position, 2 hours postprandial. The control group received no intervention and was placed in the same position for 20 minutes, 2 hours postprandial. The number of reflux episodes (REs) during IPV as compared to the number of REs in the control group during the 20 minutes period.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifty infants were included in each group;21 infants in the IPV group and 14 infants in the control group were diagnosed with abnormal MII\u2010pH (<jats:italic>P<\/jats:italic>\u2009=\u2009.142). During IPV, the number of REs was significantly lower than in the control group (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001). Also in the subgroups with abnormal or normal MII\u2010pH, a significantly lower number of REs during IPV was found (<jats:italic>P<\/jats:italic>\u2009=\u2009.011, <jats:italic>P<\/jats:italic>\u2009=\u2009.011 respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>IPV decreases the number of REs in infants independent of the results of MII\u2010pH.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.25045","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T21:05:41Z","timestamp":1598475941000},"page":"3139-3144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["The influence of Intrapulmonary percussive ventilation on gastroesophageal reflux in infants under the age of 1 year"],"prefix":"10.1002","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9335-3651","authenticated-orcid":false,"given":"Laure","family":"Lievens","sequence":"first","affiliation":[{"name":"Rehabilitation Research, Department of Physiotherapy, Human Physiology and Anatomy, Faculty of Physical Education and Physiotherapy Vrije Universiteit Brussel Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1862-8651","authenticated-orcid":false,"given":"Yvan","family":"Vandenplas","sequence":"additional","affiliation":[{"name":"KidZ Health Castle, UZ Brussel Vrije Universiteit Brussel Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6091-3675","authenticated-orcid":false,"given":"Sylvie","family":"Vanlaethem","sequence":"additional","affiliation":[{"name":"Physiotherapy Department UZ Brussel Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1565-7817","authenticated-orcid":false,"given":"Filip","family":"Van Ginderdeuren","sequence":"additional","affiliation":[{"name":"Rehabilitation Research, Department of Physiotherapy, Human Physiology and Anatomy, Faculty of Physical Education and Physiotherapy Vrije Universiteit Brussel Brussels Belgium"},{"name":"KidZ Health Castle, UZ Brussel Vrije Universiteit Brussel Brussels Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,9,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000001889"},{"issue":"8","key":"e_1_2_7_3_1","first-page":"705","article-title":"Diagnosis and treatment of gastroesophageal reflux in infants and children","volume":"92","author":"Baird DC","year":"2015","journal-title":"Am Fam Physician"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/20469047.2018.1489649"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/1817-1737.53347"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.5223\/pghn.2014.17.1.13"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23218"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21112"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23495"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23400"},{"issue":"3","key":"e_1_2_7_11_1","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/00005176-198506000-00006","article-title":"Seventeen\u2010hour continuous esophageal pH monitoring in the newborn: Evaluation of the influence of position in asymptomatic and symptomatic babies","volume":"4","author":"Vandenplas Y","year":"1985","journal-title":"J Pediatr Gastroenterol Nutr"},{"issue":"2","key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/00005176-198803000-00003","article-title":"Incidence of gastroesophageal reflux in sleep, awake, fasted, and postcibal periods in asymptomatic and symptomatic infants","volume":"7","author":"Vandenplas Y","year":"1988","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12042"},{"issue":"4","key":"e_1_2_7_14_1","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1542\/peds.88.4.834","article-title":"Gastroesophageal reflux, as measured by 24\u2010hour pH monitoring, in 509 healthy infants screened for risk of sudden infant death syndrome","volume":"88","author":"Vandenplas Y","year":"1991","journal-title":"Pediatrics"},{"issue":"4","key":"e_1_2_7_15_1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1097\/00005176-199205000-00017","article-title":"A standardized protocol for the methodology of esophageal pH monitoring and interpretation of the data for the diagnosis of gastroesophageal reflux. Working Group of the European Society of Pediatric Gastroenterology and Nutrition","volume":"14","author":"Vandenplas YBD","year":"1992","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21524"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24135"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000395"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(83)80578-2"},{"issue":"10","key":"e_1_2_7_20_1","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1007\/s11605-016-3192-1","article-title":"Inhaled beta agonist bronchodilator does not affect trans\u2010diaphragmatic pressure gradient but decreases lower esophageal sphincter retention pressure in patients with chronic obstructive pulmonary disease (COPD) and gastroesophageal reflux disease (GERD)","volume":"20","author":"Del Grande LM","year":"2016","journal-title":"JGastrointest Surg"},{"issue":"1","key":"e_1_2_7_21_1","first-page":"25","article-title":"Gastroesophageal reflux and ventilation with continuous positive pressure. Experimental study","volume":"9","author":"Eizaguirre I","year":"1996","journal-title":"Cir Pediatr"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0107736"},{"issue":"3","key":"e_1_2_7_23_1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1136\/gut.40.3.370","article-title":"Characterisation of relaxation of the lower oesophageal sphincter in healthy premature infants","volume":"40","author":"Omari TI","year":"1997","journal-title":"Gut"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70106-4"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.4.475"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0146742"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2018.02.003"},{"issue":"5","key":"e_1_2_7_28_1","doi-asserted-by":"crossref","first-page":"G1200","DOI":"10.1152\/ajpgi.00476.2006","article-title":"The impact of continuous positive airway pressure on the lower esophageal sphincter","volume":"292","author":"Shepherd KL","year":"2007","journal-title":"Am J Physiol GastrointestLiver Physiol"},{"issue":"9","key":"e_1_2_7_29_1","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.4187\/respcare.01498","article-title":"Upright positive expiratory pressure therapy and exercise: Effects on gastroesophageal reflux in COPD and bronchiectasis","volume":"57","author":"Lee AL","year":"2012","journal-title":"Respir Care"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000159378.97509.8D"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.40268.x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/0009922815603675"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21365"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.25045","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ppul.25045","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.25045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T10:40:54Z","timestamp":1693910454000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.25045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,21]]},"references-count":32,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["10.1002\/ppul.25045"],"URL":"https:\/\/doi.org\/10.1002\/ppul.25045","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"type":"print","value":"8755-6863"},{"type":"electronic","value":"1099-0496"}],"subject":[],"published":{"date-parts":[[2020,9,21]]},"assertion":[{"value":"2019-10-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}