{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T19:22:20Z","timestamp":1791832940645,"version":"4.3.4"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T00:00:00Z","timestamp":1608681600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,12,23]],"date-time":"2020-12-23T00:00:00Z","timestamp":1608681600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Esophageal atresia with tracheoesophageal fistula (EA\/TEF) is associated with many congenital and vascular malformations; however, reports utilizing computed tomography (CT) and computed tomography angiography (CTA) are limited. The objective of this study is to review CT scans of the chest from patients with EA\/TEF and report their pulmonary and vascular findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We completed a retrospective chart review of children with congenital EA\/TEF evaluated in the aerodigestive clinic at Children's Hospital Colorado. Results of the most recent CTA or CT of the chest were investigated. Demographics, medical conditions, and bronchoscopy findings were also recorded. The ratio of tracheal lumen area between inspiratory and expiratory CTA images was measured.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the patients with congenital EA\/TEF seen in the program, 47 patients had a chest CT available for review. Eight patients (17%) had bronchiectasis. Of the contrast CT scans, 15 (58%) had a vascular abnormality and 16 (62%) demonstrated tracheal compression (38% at the level of the innominate artery, 35% from other structures). Nineteen of the CTAs had volumetric expiratory images of the trachea to evaluate tracheomalacia. The mean expiratory:inspiratory area was 0.57 (\n                      <jats:italic>SD<\/jats:italic>\n                      \u2009\u00b1\u20090.23) at the level of the innominate.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients with EA\/TEF frequently have vascular abnormalities that may alter airway mechanics as well as pulmonary comorbidities that may affect long\u2010term management. For patients experiencing persistent respiratory symptoms, CTA of the chest should be considered adjunct to bronchoscopy to help with medical and surgical management of these children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.25219","type":"journal-article","created":{"date-parts":[[2020,12,10]],"date-time":"2020-12-10T18:03:30Z","timestamp":1607623410000},"page":"571-577","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Vascular and pulmonary comorbidities in children with congenital EA\/TEF"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5229-2418","authenticated-orcid":false,"given":"Thomas S.","family":"Poore","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"},{"name":"Section of Pulmonology and Sleep Medicine, The Breathing Institute Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason P.","family":"Weinman","sequence":"additional","affiliation":[{"name":"Section of Pulmonology and Sleep Medicine, The Breathing Institute Children's Hospital Colorado Aurora Colorado USA"},{"name":"Division of Pediatric Radiology,\u00a0Department of Radiology University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyse","family":"Handley","sequence":"additional","affiliation":[{"name":"Division of Pediatric Otolaryngology,\u00a0Department of Otolaryngology University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Wine","sequence":"additional","affiliation":[{"name":"Division of Pediatric Otolaryngology,\u00a0Department of Otolaryngology University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sparrow","family":"Helland","sequence":"additional","affiliation":[{"name":"Section of Pulmonology and Sleep Medicine, The Breathing Institute Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Corbett","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"},{"name":"Section of Pulmonology and Sleep Medicine, The Breathing Institute Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Antoniolli","sequence":"additional","affiliation":[{"name":"Section of Pulmonology and Sleep Medicine, The Breathing Institute Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stig","family":"Somme","sequence":"additional","affiliation":[{"name":"Division of Pediatric Surgery,\u00a0Department of Surgery University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Friedlander","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"},{"name":"Section of Gastroenterology, Digestive Health Institute Children's Hospital Colorado Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy D","family":"Prager","sequence":"additional","affiliation":[{"name":"Division of Pediatric Otolaryngology,\u00a0Department of Otolaryngology University of Colorado School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0924-9342","authenticated-orcid":false,"given":"Emily M.","family":"DeBoer","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"},{"name":"Section of Pulmonology and Sleep Medicine, The Breathing Institute Children's Hospital Colorado Aurora Colorado 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