{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T04:48:34Z","timestamp":1785386914005,"version":"3.55.0"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Long\u2010term respiratory consequences of bronchopulmonary dysplasia (BPD) in preterm infants born in the post\u2010surfactant era (\u201cnew\u201d BPD) remain partially unknown. The present study aimed to evaluate the respiratory outcomes of \u201cnew\u201d BPD in adolescents who were born preterm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This multicenter, cross\u2010sectional study included 286 adolescents born between 2003 and 2005 (mean age: 14.2\u2009years); among them, 184 and 102 were born extremely preterm (EP; &lt;28\u2009weeks' gestation) and moderate\u2013late preterm (32 to &lt;37\u2009weeks' gestation), respectively. Among EP adolescents, 92 had BPD, and 92 did not. All participants underwent lung function tests, skin prick testing, and questionnaires on asthma symptoms and quality of life.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>EP adolescents with BPD had significantly lower forced expiratory volume in 1\u2009s (FEV<jats:sub>1<\/jats:sub>), forced vital capacity (FVC), FEV<jats:sub>1<\/jats:sub>\/FVC ratio, and forced expiratory flow between 25% and 75% of FVC than other included adolescents. FEV<jats:sub>1<\/jats:sub>\/FVC ratios were below the lower limit of normal (<jats:italic>z<\/jats:italic>\u2010score &lt;\u22121.645) in 30.4% of EP adolescents with BPD, 13.0% of EP adolescents without BPD, and 11.8% of adolescents who were born moderate\u2013late preterm. Bronchodilator response and air\u2010trapping were significantly higher in BPD adolescents than in other adolescents. Diffusion capacity was significantly lower in EP adolescents than in moderate\u2013late preterm adolescents. Asthma symptoms and quality\u2010of\u2010life scores were similar among groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>EP adolescents with \u201cnew\u201d BPD had poorer pulmonary function than EP adolescents without BPD or moderate\u2013late preterm adolescents. Further studies are needed to determine whether \u201cnew\u201d BPD is associated with early\u2010onset chronic obstructive pulmonary disease in adulthood.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.25226","type":"journal-article","created":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T11:31:31Z","timestamp":1607945491000},"page":"1205-1214","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Respiratory outcomes of \u201cnew\u201d bronchopulmonary dysplasia in adolescents: A multicenter study"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0341-5979","authenticated-orcid":false,"given":"Santiago","family":"P\u00e9rez\u2010Tarazona","sequence":"first","affiliation":[{"name":"Division of Neonatology La Fe University and Polytechnic Hospital  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Rueda 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