{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T17:19:26Z","timestamp":1781716766658,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The treatment of extralobar pulmonary sequestration (ELS) remains divergent. This study aims to demonstrate the characters of ELS in children for optimal clinical management in the future.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and Methods<\/jats:title><jats:p>A retrospective analysis was conducted for ELS patients' treatment in our center from January 2013 to April 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 85 patients were included, containing 70 upper\u2010diaphragmatic, 7 intra\u2010diaphragmatic, and 8 infra\u2010diaphragmatic ELS. Eight patients' pathology results showing inflammation without symptoms preoperation and two patients had chest pain for torsion. All the upper\u2010diaphragmatic and intra\u2010diaphragmatic ELS patients accepted thoracoscopic surgery resection. The intraoperative operation time and blood loss volume of intra\u2010diaphragmatic ELS were significantly more than that of the upper\u2010diaphragmatic (40.14\u2009\u00b1\u20099.92\u2009 vs. 23.07\u2009\u00b1\u20096.79\u2009min; 9.29\u2009\u00b1\u20093.45\u2009 vs. 3.18\u2009\u00b1\u20094.94\u2009ml; all <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). No chest tubes were inserted in both subgroups. No complications were found in the postoperative follow\u2010up of operative ELS patients at least 3 months. A total of eight infra\u2010diaphragmatic ELS patients except for one (7\/8) had conservative therapy and follow\u2010up by the outpatient clinic or phone call eventually. There were no symptoms occurring and no size increasing of observation infra\u2010diaphragmatic ELS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The ELS has the potential risk of infection and torsion in this study. Thoracoscopic surgery might be optimal management of upper\u2010diaphragmatic ELS for its minimal invasion and low perioperative risks, which could be developed into a day operation with safe and quick recovery. The intra\u2010diaphragmatic and infra\u2010diaphragmatic ELS need a larger sample size and multiple center data to get a better management approach.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.25433","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T20:08:48Z","timestamp":1619813328000},"page":"2322-2327","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The clinical management of extralobar pulmonary sequestration in children"],"prefix":"10.1002","volume":"56","author":[{"given":"Dongmei","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Pediatric Thoracic Surgery, Guangzhou Women and Children's Medical Center Guangzhou Medical University  Guangzhou Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aerxin","family":"\uff65\u00a0Habuding","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery 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