{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T07:17:35Z","timestamp":1776842255456,"version":"3.51.2"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T00:00:00Z","timestamp":1624579200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Among infants needing urgent transfer after birth, very preterm infants are a high\u2010risk sub\u2010group requiring special attention. This study aimed to assess trends in early respiratory management in a large series of very preterm infants undergoing postnatal transfer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Trends in patient characteristics and early respiratory management were assessed in 798 very preterm infants who were transferred by the Eastern Veneto Neonatal Emergency Transport Service in 2000\u20132019. Trends were analyzed using joinpoint regression analysis and summarized as annual percentage changes (APCs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Proportion of neonates with birth weight less than 1\u2009kg decreased from 33% to 16% (APC \u22123.82%). Use of nasal\u2010continuous\u2010positive\u2010airway pressure increased (at call: APC 15.39%; during transfer: APC 15.60%), while use of self\u2010inflating bag (at call: APC \u221212.09%), oxygen therapy (at call: APC \u221213.00%; during transfer: APC \u221223.77%) and mechanical ventilation (at call: APC \u22122.71%; during transfer: APC \u22122.99%) decreased. Use of oxygen concentrations at 21% increased (at call: APC 6.26%; during transfer: APC 7.14%), while oxygen concentrations above 40% decreased (at call: APC \u22125.73%; at transfer APC \u22128.89%). Surfactant administration at call increased (APC 3%\u201310%), while surfactant administration when arriving at referring hospital remained around 7\u201011% (APC 2.55%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Relevant trends toward \u201cgentle\u201d approaches in early respiratory management of very preterm infants undergoing postnatal transfer occurred during the last twenty years. In addition, the proportion of transferred extremely low birth weight infants halved. Clinicians and stakeholders should consider such information when allocating assets to both hospitals and transfer services and planning regional perinatal programs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.25532","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T20:00:51Z","timestamp":1624651251000},"page":"2604-2610","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Trends in respiratory management of transferred very preterm infants in the last two decades"],"prefix":"10.1002","volume":"56","author":[{"given":"Francesco","family":"Cavallin","sequence":"first","affiliation":[{"name":"Independent statistician  Solagna Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicoletta","family":"Doglioni","sequence":"additional","affiliation":[{"name":"Department of Woman and Child Health University Hospital of Padova  Padova 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