{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T21:28:39Z","timestamp":1771363719019,"version":"3.50.1"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T00:00:00Z","timestamp":1627862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Long\u2010term home noninvasive ventilation (NIV) is increasingly employed in children with sleep\u2010disordered breathing and chronic respiratory failure. While studies suggest its successful implementation in tertiary care centers, little is known about the situation in a general care setting. Hence, we aim to evaluate the clinical profiles of these children in a general pediatric unit over the past two decades.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data collected retrospectively on patients younger than 18 years old receiving long\u2010term home NIV from January 1, 1997 to December 31, 2017 in a Hong Kong regional general pediatric unit were reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The number of children on home NIV increased more than 10\u2010fold over the past two decades. In total, 114 children were commenced on NIV during the 21\u2010year period. Upper airway obstruction was the most common cause (77%), followed by neuromuscular diseases (16%), pulmonary disorders (4%), and abnormal ventilatory control (3%). Continuous positive airway pressure was the most common NIV type (59%). To date, 46% of the children remained in our NIV program, while 18% discontinued NIV support. NIV adherence increased significantly with follow\u2010up (median of 78.6% and 82.5% at baseline and last follow\u2010up, respectively). Sixty\u2010five percent of the children used NIV for at least 4\u2009h on 70% of the days monitored. Higher body mass index was associated with lower adherence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Pediatric home NIV is feasible in the general care setting with good outcomes and adherence. As the demand for NIV service grows, input from local hospitals will be of increasing importance and should be considered upon healthcare planning.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.25593","type":"journal-article","created":{"date-parts":[[2021,8,2]],"date-time":"2021-08-02T20:56:08Z","timestamp":1627937768000},"page":"3349-3357","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Feasibility of long\u2010term home noninvasive ventilation program in a general pediatric unit: 21 years' experience in Hong Kong"],"prefix":"10.1002","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7816-3262","authenticated-orcid":false,"given":"Yuk\u2010Ping","family":"Tsang","sequence":"first","affiliation":[{"name":"Department of Paediatrics Kwong Wah Hospital Hong Kong Hong Kong SAR"},{"name":"Department of Paediatrics &amp; Adolescent Medicine United Christian Hospital Kowloon Hong Kong 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