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Several hypothetical mechanisms have been proposed to unify the coexistence of these two entities, also referred to as Lane\u2010Hamilton syndrome (LHS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>This manuscript is a scoping review of the medical literature. Medline, Embase, and PubMed Central databases were searched between 1971 and 2021 with appropriate search words to identify all cases of pediatric LHS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 20 manuscripts with 23 pediatric patients with LHS were identified. The mean age was 11 years, and 13\/23 (56.5%) of the children were boys. Hemoptysis was present in 57% of patients during diagnosis. Bronchoscopy with bronchoalveolar lavage demonstrating hemosiderin laden macrophages was the primary mode of diagnostic confirmation. Only three patients underwent lung biopsy. Any significant GI symptom was reported in a minority of patients (22%). Iron deficiency anemia on presentation was described in 83% of children. The majority of patients were malnourished. Serology for CD was positive in all patients, as was the histopathologic analysis of the small bowel biopsy. No patients had any other autoantibody positivity. The introduction of gluten free diet (GFD) was associated with a positive response in 20\/23 patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>All pediatric patients with IPH should undergo screening for CD. Low serum ferritin in patients with IPH could be suggestive of coexisting CD. Strict GFD should be tried as the initial therapy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.25847","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T06:09:32Z","timestamp":1643350172000},"page":"1127-1144","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Association between idiopathic pulmonary hemosiderosis and celiac disease in pediatric patients: A scoping review of the literature over the past 50 years"],"prefix":"10.1002","volume":"57","author":[{"given":"Biplab K","family":"Saha","sequence":"first","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine Ozarks Medical Center West Plains Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santu","family":"Saha","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Bangladesh Medical College Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyssa","family":"Bonnier","sequence":"additional","affiliation":[{"name":"Department of Critical Care Nursing, Goldfarb School of Nursing Barnes Jewish College St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baidya Nath","family":"Saha","sequence":"additional","affiliation":[{"name":"Department of Medicine Saha Clinic Narail Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"e_1_2_22_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/crj.12440"},{"key":"e_1_2_22_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-021-05895-1"},{"key":"e_1_2_22_4_1","first-page":"8137648","article-title":"A case of acute life\u2010threatening pulmonary hemorrhage from synthetic cannabinoid abuse","volume":"2019","author":"Imtiaz M","year":"2019","journal-title":"Case Rep Pulmonol"},{"issue":"4","key":"e_1_2_22_5_1","first-page":"e14714","article-title":"Unilateral diffuse alveolar hemorrhage due to selective directionality of mitral regurgitant jet in a patient with severe aortic stenosis","volume":"13","author":"Saha S","year":"2021","journal-title":"Cureus"},{"key":"e_1_2_22_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-021-00433-x"},{"issue":"7","key":"e_1_2_22_7_1","first-page":"902","article-title":"Idiopathic pulmonary haemosiderosis","volume":"92","author":"Milman N","year":"1998","journal-title":"Epidemiology, pathogenic aspects and diagnosis. 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