{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T08:31:15Z","timestamp":1770280275366,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T00:00:00Z","timestamp":1647475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To study the clinical characteristics and impact of bronchoscopy in children from developing countries, referred for cardiac surgery, through the \"Save a Child's Heart\" (SACH) organization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective hospital\u2010chart review of SACH children (0\u201318 years old) referred between 2006 and 2021 who underwent fiberoptic bronchoscopy. We examined demographics, congenital\u2010heart\u2010disease (CHD) types, bronchoscopy's indications and findings, subsequent recommendations, number of ventilation, and intensive\u2010care\u2010unit days. The primary outcome was percent changes in management and diagnosis, following the bronchoscopy. We included a control group matched\u2010for\u2010age and CHD type, who did not undergo bronchoscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We performed 82 bronchoscopies in 68 children: 18 (26.5%) preoperatively; 46 (67.6%) postoperatively; and four (5.9%) both. The most prevalent CHDs were Tetralogy\u2010of\u2010Fallot (27.9%) and ventricular\u2010septal\u2010defect (19.1%). The main indications were persistent atelectasis (41%) and mechanical ventilation\/weaning difficulties (27.9%). Bronchoscopic evaluations revealed at least one abnormality in 51\/68 (75%) children. The most common findings were external airway compression (23.5%), bronchomalacia (19.1%), and mucus secretions (14.7%). Changes in management were made in 35 (51.4%) cases, with a major change made in 14\/35 (40%) children. Compared to the control group, the children undergoing bronchoscopy were both ventilated longer (median 6 vs. 1.5 days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) and stayed longer in the intensive care unit (median 1.5 vs. 18.5 days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A bronchoscopy is an important tool in the diagnosis and management of the unique group of children from developing countries with CHD referred for cardiac surgery. The results of our study, reveal a more complicated clinical course in children requiring bronchoscopy compared to controls.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.25869","type":"journal-article","created":{"date-parts":[[2022,2,25]],"date-time":"2022-02-25T04:33:03Z","timestamp":1645763583000},"page":"1196-1201","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Bronchoscopy in the management of children from developing countries undergoing congenital heart surgery"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3430-3873","authenticated-orcid":false,"given":"Michael","family":"Schnapper","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Sylvan Adams Children's Hospital E. Wolfson Medical Center Holon Israel"},{"name":"Sackler Faculty of Medicine Tel\u2010Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan","family":"Dalal","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Sylvan Adams Children's Hospital E. Wolfson Medical Center Holon Israel"},{"name":"Sackler Faculty of Medicine Tel\u2010Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8782-3779","authenticated-orcid":false,"given":"Avigdor","family":"Mandelberg","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel\u2010Aviv University Tel Aviv Israel"},{"name":"Pediatric Pulmonology Unit Sylvan Adams Children's Hospital, E. Wolfson Medical Center Holon Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alona","family":"Raucher Sternfeld","sequence":"additional","affiliation":[{"name":"Pediatric Cardiology Unit Sylvan Adams Children's Hospital, E. Wolfson Medical Center Holon Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lior","family":"Sasson","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Sylvan Adams Children's Hospital, E. Wolfson Medical Center Holon Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1191-1697","authenticated-orcid":false,"given":"Keren","family":"Armoni Domany","sequence":"additional","affiliation":[{"name":"Sackler Faculty of Medicine Tel\u2010Aviv University Tel Aviv Israel"},{"name":"Pediatric Pulmonology Unit Sylvan Adams Children's Hospital, E. Wolfson Medical Center Holon Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyz009"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","unstructured":"MoonsP BovijnL BudtsW BelmansA GewilligM.\u00a0Temporal trends in survival to adulthood among patients born with congenital heart disease from 1970 to 1992 in Belgium.Circulation.2010;122(22):2264\u20102272.","DOI":"10.1161\/CIRCULATIONAHA.110.946343"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(20)31466-5"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9592.2003.01192.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0137437"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001340051285"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198208000-00009"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2003.07.034"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.08.039"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951107000145"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2016.69.1.71"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-014-0875-9"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2020.09.089"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/PHH.0000000000000348"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10071-23419"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10164"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20910"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951119000301"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23732"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.10.149"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41372-018-0280-y"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-0770(98)90321-4"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.25869","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ppul.25869","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.25869","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T07:17:42Z","timestamp":1692688662000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.25869"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,17]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1002\/ppul.25869"],"URL":"https:\/\/doi.org\/10.1002\/ppul.25869","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,17]]},"assertion":[{"value":"2022-01-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}