{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T04:12:49Z","timestamp":1768450369841,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T00:00:00Z","timestamp":1653091200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>High\u2010flow nasal therapy (HFNT) is a safe and simple way to deliver humidified air and oxygen for respiratory support in infants and children. HFNT is well established in an inpatient setting, but home HFNT lacks evidence. In the current study, we studied characteristics and outcomes of pediatric patients with home HFNT.\u00a0In a monocentric retrospective analysis of data for 10 years (April 2010\u2013April 2020), patient characteristics from the time point of the first discharge from hospital with home HFNT\u2010treatment and the subsequent course were analyzed. Patients were divided into three HFNT indication groups: (1) bronchopulmonary dysplasia (BPD),\u00a0(2) upper airway obstruction (UAO), and (3) other indications.\u00a0Forty patients received home HFNT in the study period. Seventeen patients were treated for BPD, 15 for UAO, and 8 had other indications. Twenty\u2010two\u00a0patients (55%) were successfully weaned from HFNT (12 [70.6%] BPD, 7 [46.7%] UAO, 3 [37.5%] other), while seven patients (17.5%) died during follow\u2010up (4 BPD, 2 UAO, 1 other). Twenty\u2010three patients (57.5%) required (intermittent) additional oxygen application (14 [82.4%] BPD, 6 [40%] UAO, 4 [50%] other). Weaning success and need for additional oxygen were significantly more probable in BPD patients compared to the UOA group. In conclusion, HFNT plays an increasing role in home treatment of respiratory insufficiency of various etiologies in childhood. It often represents a temporary intervention, especially for children with BPD but might also serve as long\u2010term treatment for children in whom other forms of ventilatory support are not feasible or desired.<\/jats:p>","DOI":"10.1002\/ppul.25974","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T08:50:15Z","timestamp":1652691015000},"page":"2048-2052","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Indications and outcome of home high\u2010flow nasal therapy in children, a single\u2010center experience"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2724-5297","authenticated-orcid":false,"given":"Mathis","family":"Steindor","sequence":"first","affiliation":[{"name":"Division of Pediatric Pulmonology and Sleep Medicine,\u00a0Department of Pediatrics III, Children's Hospital University of Duisburg\u2010Essen Essen 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Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarete","family":"Olivier","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology and Sleep Medicine,\u00a0Department of Pediatrics III, Children's Hospital University of Duisburg\u2010Essen Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Florian","family":"Stehling","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology and Sleep Medicine,\u00a0Department of Pediatrics III, Children's Hospital University of Duisburg\u2010Essen Essen 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