{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:53:27Z","timestamp":1786978407953,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,5,27]],"date-time":"2022-05-27T00:00:00Z","timestamp":1653609600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The natural history of cystic fibrosis (CF) lung disease is a chronic deterioration of lung function with intermittent episodes of pulmonary infectious exacerbations (PExs). Reliable venous access is a milestone of effective management of such exacerbations, managed both in hospital and outpatient chronic therapy. The aim of our study was to analyze the feasibility of ultrasound\u2010guided positioning of long peripheral catheters (LPC) as reliable midterm venous access in children affected by CF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this single\u2010center prospective study, over a 60\u2010month period, we included paediatric CF subjects admitted with PExs\u00a0and undergoing intravenous antibiotic treatment. LPCs were inserted in all participants by paediatric anaesthesiologists with ultrasound guide technique. Prospective data were collected assessing catheter positioning procedure and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 122 LPC insertions were performed in 55 CF children. Participants had a median age of 6.75 years (interquatile range:\u00a03.7\u221213.5) at the time of catheter insertion. Implantation was successful on the first attempt in 86% of cases; 2 (1%) major insertion\u2010related complications were reported. Eighty\u2010eight percent\u00a0of catheters were electively removed at the end of antibiotic therapy without any complication. Seven percent\u00a0of the catheters were removed electively for occlusion and 2% for local dislodgment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of the present study suggest that ultrasound\u2010guided positioning of LPCs are safe alternative means of peripheral venous access in children with chronic diseases such as CF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.25978","type":"journal-article","created":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T04:33:37Z","timestamp":1652675617000},"page":"2060-2066","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Ultrasound\u2010guided placement of long peripheral cannula in children with cystic fibrosis"],"prefix":"10.1002","volume":"57","author":[{"given":"Massimiliano","family":"Giardina","sequence":"first","affiliation":[{"name":"Division of Anesthesia and Critical Care A. O. U. Policlinico \"G. Martino\u201d Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Barill\u00e0","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Unit of Vascular Surgery, Policlinico G. Martino University of Messina Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Crimi","sequence":"additional","affiliation":[{"name":"Respiratory Medicine Unit, Policlinico \u201cG. Rodolico\u2010San Marco\u201d University Hospital Catania Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelia","family":"Arone","sequence":"additional","affiliation":[{"name":"IRCCS Policlinico San Donato San Donato Milanese Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo","family":"Benedetto","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Unit of Vascular Surgery, Policlinico G. Martino University of Messina Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Lucanto","sequence":"additional","affiliation":[{"name":"Regional Centre for Cystic Fibrosis A. O. U. Policlinico G.Martino Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rossella","family":"Natoli","sequence":"additional","affiliation":[{"name":"School of Medicine and Surgery University of Milano\u2010Bicocca Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Messina","sequence":"additional","affiliation":[{"name":"Division of Anesthesia and Critical Care A. O. U. Policlinico \"G. Martino\u201d Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"David","sequence":"additional","affiliation":[{"name":"Department of Human Pathology of the Adult and Evolutive Age \u201cGaetano Barresi\u201d, Division of Anesthesia and Critical Care University of Messina Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Noto","sequence":"additional","affiliation":[{"name":"Department of Human Pathology of the Adult and Evolutive Age \u201cGaetano Barresi\u201d, Division of Anesthesia and Critical Care University of Messina Messina Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,5,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMe020070"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201009-1478CI"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.25122\/jml-2020-0011"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1698464"},{"key":"e_1_2_10_6_1","doi-asserted-by":"crossref","unstructured":"AbbottL PlummerA HooZH WildmanM.Duration of intravenous antibiotic therapy in people with cystic fibrosis.Cochrane Database Syst Rev.2019;2019(9).","DOI":"10.1002\/14651858.CD006682.pub6"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202102-0461OC"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2019-3474I"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijnurstu.2013.09.002"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.14229"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66878-X"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1129729818761278"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1129729820927272"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/135910539800300103"},{"key":"e_1_2_10_15_1","doi-asserted-by":"crossref","unstructured":"MorosiniI LucentiE MozzarelliF RaffoE.Mini\u2010midline a new device for peripheral venous catheterization UN emergency wards.J Anest & Inten Care Med.2018;6(1):555678.doi:10.19080\/JAICM.2018.06.555678","DOI":"10.19080\/JAICM.2018.06.555678"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.5301\/jva.5000274"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjpo-2017-000244"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.17659"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2015.8402"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001707"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1542\/hpeds.2020-0181"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.12788\/jhm.3313"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0000000000000272"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(96)03163-6"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/0009922811435164"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-021-03930-6"},{"key":"e_1_2_10_27_1","doi-asserted-by":"crossref","unstructured":"de laVieja\u2010SorianoM Blanco\u2010DazaM Macip\u2010BelmonteS Dominguez\u2010Mu\u00f1ozM L\u00f3pez\u2010S\u00e1nchezE P\u00e9rez\u2010P\u00e9rezE.Difficult intravenous access in a paediatric intensive care unit..Enferm Intensiva.2021; 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