{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T13:16:07Z","timestamp":1783948567640,"version":"3.55.0"},"reference-count":40,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T00:00:00Z","timestamp":1657238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI20\/00095"],"award-info":[{"award-number":["PI20\/00095"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pneumonia is a frequent manifestation of coronavirus disease 2019 (COVID\u201019) in hospitalized children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study involved 80 hospitals in the severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) Spanish Pediatric National Cohort. Participants were children &lt;18 years, hospitalized with SARS\u2010CoV\u20102 community\u2010acquired pneumonia (CAP). We compared the clinical and radiological characteristics of SARS\u2010CoV\u20102\u2010associated CAP with CAP due to other viral etiologies from ValsDance (retrospective) cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total, 151 children with SARS\u2010CoV\u20102\u2010associated CAP and 138 with other viral CAP were included. Main clinical features of SARS\u2010CoV\u20102\u2010associated CAP were cough, fever, or dyspnea. Lymphopenia was found in 43% patients and 15% required admission to the pediatric intensive care unit (PICU). Chest X\u2010ray revealed condensation (42%) and other infiltrates (58%). Compared with CAP from other viral pathogens, COVID\u201019 patients were older, with lower C\u2010reactive protein (CRP) levels, less wheezing, and greater need of mechanical ventilation (MV). There were no differences in the use of continuous positive airway pressure (CPAP) or HVF, or PICU admission between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>SARS\u2010CoV\u20102\u2010associated CAP in children presents differently to other virus\u2010associated CAP: children are older and rarely have wheezing or high CRP levels; they need less oxygen but more CPAP or MV. However, several features overlap and differentiating the etiology may be difficult. The overall prognosis is good.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.26042","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T03:28:56Z","timestamp":1656300536000},"page":"2374-2382","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of pneumonia features in children caused by SARS\u2010CoV\u20102 and other viral respiratory pathogens"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8740-7601","authenticated-orcid":false,"given":"Rut","family":"del Valle","sequence":"first","affiliation":[{"name":"Pediatrics Department, Pediatrics Research Group, Hospital Universitario Infanta Sof\u00eda Universidad Europea de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1lvaro","family":"Ballesteros","sequence":"additional","affiliation":[{"name":"Pediatric Research and Clinical Trials Unit (UPIC), 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