{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T11:38:12Z","timestamp":1783597092952,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,8,17]],"date-time":"2022-08-17T00:00:00Z","timestamp":1660694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation","doi-asserted-by":"publisher","award":["KASS20D0"],"award-info":[{"award-number":["KASS20D0"]}],"id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>There is evidence for increased risk of eating disorders in individuals with diet\u2010treated chronic illnesses, however, data in patients with cystic fibrosis (CF) is less clear. No studies have evaluated avoidant\/restrictive food intake disorder (ARFID) in the CF population. We investigated the prevalence of eating disorders, including ARFID, in adolescents and young adults with CF.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with CF aged 14\u201335 years were recruited to complete three validated surveys: (1) Eating Disorder Examination Questionnaire (EDE\u2010Q), (2) Nine\u2010Item Avoidant\/Restrictive Food Intake Disorder Scale (NIAS), and (3) Cystic Fibrosis Questionnaire\u2010Revised (CFQ\u2010R). Univariate linear regression analysis identified baseline risk factors associated with these survey scores. Variables with univariate <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.20 were considered for inclusion in a multivariable linear regression model. Backwards stepwise linear regression was used to identify the final model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 52 patients enrolled. The prevalence of a positive screen on the EDE\u2010Q was 9.6%, and on the NIAS was 13.5%. The CFQ\u2010R eating and weight subscales were associated with scores on the EDE\u2010Q, and CFQ\u2010R eating subscale and being dF508 homozygous were correlated with the NIAS total score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>A clinically significant number of participants screened positive for eating disorders on the EDE\u2010Q and NIAS. Scores on the eating and weight scales of the CFQ\u2010R were associated with the scores on these surveys. Further work is needed to better understand the optimal way to use such tools to screen and treat for eating disorders in individuals with CF.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.26102","type":"journal-article","created":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T02:52:45Z","timestamp":1659754365000},"page":"2791-2797","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Eating disorders in adolescents and young adults with cystic fibrosis"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1814-9108","authenticated-orcid":false,"given":"Alexandra P.","family":"Kass","sequence":"first","affiliation":[{"name":"Division of Pediatric Pulmonology Columbia University Irving Medical Center New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Berbert","sequence":"additional","affiliation":[{"name":"Boston Children's Hospital Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5139-831X","authenticated-orcid":false,"given":"Suzanne","family":"Dahlberg","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elana","family":"Bern","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Sabharwal","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Leonard","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Hepatology, and Nutrition Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Richmond","sequence":"additional","affiliation":[{"name":"Division of Adolescent\/Young Adult Medicine Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3356-709X","authenticated-orcid":false,"given":"Gregory S.","family":"Sawicki","sequence":"additional","affiliation":[{"name":"Division of Pulmonary Medicine Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,8,17]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Cystic Fibrosis Foundation. 2020 Patient Registry Annual Data Report.2020."},{"key":"e_1_2_9_3_1","unstructured":"Cystic Fibrosis Foundation. Nutritional Basics. Accessed\u00a0October 29 2021.https:\/\/www.cff.org\/Life-With-CF\/Daily-Life\/Fitness-and-Nutrition\/Nutrition\/Getting-Your-Nutrients\/Nutritional-Basics\/"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(88)90063-7"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-207488"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","unstructured":"ConviserJH SheehanP MccolleySA. Are children with chronic illnesses requiring dietary therapy at risk for disordered eating or eating disorders? 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