{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T21:52:44Z","timestamp":1780350764204,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T00:00:00Z","timestamp":1663545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100015763","name":"Szegedi Tudom\u00e1nyegyetem","doi-asserted-by":"publisher","award":["EFOP\u20103.6.2\u201016\u20102017\u201000006"],"award-info":[{"award-number":["EFOP\u20103.6.2\u201016\u20102017\u201000006"]}],"id":[{"id":"10.13039\/501100015763","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015763","name":"Szegedi Tudom\u00e1nyegyetem","doi-asserted-by":"publisher","award":["GINOP 2.3.2.\u201015\u20102016\u201000048"],"award-info":[{"award-number":["GINOP 2.3.2.\u201015\u20102016\u201000048"]}],"id":[{"id":"10.13039\/501100015763","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Obstructive sleep apnea (OSA) appears in 2%\u20135% of children, with first\u2010line treatment being adenotonsillar (AT) surgery. Our aim was to examine the risk of postoperative respiratory complications (PoRCs) in non\u2010OSA and the different OSA severity (mild, moderate, severe) groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>We conducted a systematic review and meta\u2010analysis of studies comparing PoRCs following AT surgery in children with and without OSA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nineteen observational studies were identified with the same search key used in MEDLINE, Embase, and CENTRAL. The connection between PoRCs, the presence and severity of OSA, and additional comorbidities were examined. Odds ratios (OR) were calculated with 95% confidence intervals (CI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found that PoRCs appeared more frequently in moderate (<jats:italic>p<\/jats:italic>\u2009=\u20090.048, OR: 1.79, CI\u00a0[1.004, 3.194]) and severe OSA (<jats:italic>p<\/jats:italic>\u2009=\u20090.002, OR: 4.06, CI\u00a0[1.68, 9.81]) compared to non\u2010OSA patients. No significant difference was detected in the appearance of major complications (<jats:italic>p<\/jats:italic>\u2009=\u20090.200, OR: 2.14, CI\u00a0[0.67, 6.86]) comparing OSA and non\u2010OSA populations. No significant difference was observed in comorbidities (<jats:italic>p<\/jats:italic>\u2009=\u20090.669, OR: 1.29, CI\u00a0[0.40, 4.14]) or in the distribution of PoRCs (<jats:italic>p<\/jats:italic>\u2009=\u20090.904, OR: 0.94, CI\u00a0[0.36, 2.45]) between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Uniform guidelines and a revision of postoperative monitoring are called for as\u00a0children with moderate and severe OSA are more likely to develop PoRCs following AT surgery based on our results, but no significant difference was found in mild OSA. Furthermore, the presence of OSA alone is not associated with an increased risk of developing major complications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.26121","type":"journal-article","created":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T20:14:02Z","timestamp":1661717642000},"page":"2889-2902","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["The risk of postoperative respiratory complications following adenotonsillar surgery in children with or without obstructive sleep apnea: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3818-5114","authenticated-orcid":false,"given":"Fanni","family":"Keser\u0171","sequence":"first","affiliation":[{"name":"Heim P\u00e1l National Paediatric Institute Budapest Hungary"},{"name":"Doctoral School of Clinical Medicine University of Szeged Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Sipos","sequence":"additional","affiliation":[{"name":"Medical School, Institute for Translational Medicine, Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelli","family":"Farkas","sequence":"additional","affiliation":[{"name":"Medical School, Institute for Translational Medicine, Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Hegyi","sequence":"additional","affiliation":[{"name":"Medical School, Institute for Translational Medicine, Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"},{"name":"Division of Pancreatic Diseases, Heart and Vascular Center, Centre for Translational Medicine Semmelweis University Budapest Hungary"},{"name":"First Department of Medicine University of Szeged Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rk F\u00e9lix","family":"Juh\u00e1sz","sequence":"additional","affiliation":[{"name":"Heim P\u00e1l National Paediatric Institute Budapest Hungary"},{"name":"Medical School, Institute for Translational Medicine, Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikt\u00f3ria Adrienn","family":"J\u00e1szai","sequence":"additional","affiliation":[{"name":"Medical School, Institute for Translational Medicine, Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"P\u00e1rniczky","sequence":"additional","affiliation":[{"name":"Heim P\u00e1l National Paediatric Institute Budapest Hungary"},{"name":"Medical School, Institute for Translational Medicine, Szent\u00e1gothai Research Centre University of P\u00e9cs P\u00e9cs Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1447-1677","authenticated-orcid":false,"given":"P\u00e1lma Edina","family":"Benedek","sequence":"additional","affiliation":[{"name":"Heim P\u00e1l National Paediatric Institute Budapest Hungary"},{"name":"Doctoral School of Clinical Medicine University of Szeged Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.109.4.e69"},{"key":"e_1_2_10_3_1","first-page":"1388","volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications","author":"Iber C","year":"2007"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-1671"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348941011900802"},{"key":"e_1_2_10_6_1","unstructured":"RieraE. 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