{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:53:28Z","timestamp":1786978408112,"version":"build-2736575974"},"reference-count":87,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The field of rare and diffuse pediatric lung disease is experiencing rapid progress as diagnostic and therapeutic options continue to expand. In this annual review, we discuss manuscripts published in\n                    <jats:italic>Pediatric Pulmonology<\/jats:italic>\n                    in 2021 in (1) children's interstitial and diffuse lung disease, (2) congenital airway and lung malformations, and (3) noncystic fibrosis bronchiectasis including primary ciliary dyskinesia. These include case reports, descriptive cohorts, trials of therapies, animal model studies, and review articles. The results are put into the context of other literature in the field. Each furthers the field in important ways, while also highlighting the continued need for further studies.\n                  <\/jats:p>","DOI":"10.1002\/ppul.26227","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T05:09:41Z","timestamp":1669352981000},"page":"374-381","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pediatric pulmonology 2021 year in review: Rare and diffuse lung disease"],"prefix":"10.1002","volume":"58","author":[{"given":"Jonathan","family":"Popler","sequence":"first","affiliation":[{"name":"Children's Physician Group\u2014Pulmonology Children's Healthcare of Atlanta Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Vece","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology and Program for Rare and Interstitial Lung Disease University of North Carolina School of Medicine Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah R.","family":"Liptzin","sequence":"additional","affiliation":[{"name":"School of Public and Community Health University of Montana Missoula Montana USA"},{"name":"Department of Pediatrics University of Colorado School of Medicine Aurora Colorado USA"},{"name":"Department of Pediatrics University of Washington School of Medicine Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5863-7379","authenticated-orcid":false,"given":"William A.","family":"Gower","sequence":"additional","affiliation":[{"name":"Division of Pediatric Pulmonology and Program for Rare and Interstitial Lung Disease University of North Carolina School of Medicine Chapel Hill North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201305-0923ST"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201501-064OC"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200703-393OC"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00805-2020"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22718"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.05.032"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2016.04.018"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25319"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201908-617OC"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20243"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201508-1655OC"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.21219"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-0811"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201603-155BC"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.38462"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2015.08.001"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-1304"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25292"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2018.09.004"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.4.1183"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-8-175"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25362"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOP.0000000000000751"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25356"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1402584"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2016.07.009"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1908681"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25684"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.02.018"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201906-1204LE"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-018-3301-0"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2021.145575"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25269"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25373"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-015-0224-7"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2019.04.011"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3746"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.02.055"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25151"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25336"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-014-0171-z"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00090610"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-019-0066-3"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2017-211076"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25174"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25166"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25547"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25617"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25128"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7869130"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25086"},{"issue":"2","key":"e_1_2_10_53_1","first-page":"e7002","article-title":"Long\u2010term impact of E\u2010cigarette and vaping product use\u2010associated lung injury on diffusing capacity for carbon monoxide values: a case series","volume":"12","author":"Ahmad M","year":"2020","journal-title":"Cureus"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32679-0"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25675"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197612162952502"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203315605365"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1183\/23120541.00081-2015"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25553"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25657"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.136119"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja14.00287"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.4103\/atm.ATM_171_17"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI73469"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25206"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25656"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1080\/01913123.2017.1362088"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201805-0819ST"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01090-2016"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23167"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25432"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25133"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25219"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27939"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25203"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.3928\/19382359-20190326-02"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2015.01.014"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2015.02.003"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24119"},{"key":"e_1_2_10_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25232"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000249444.90594.27"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25401"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-018-0390-0"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201706-1243OC"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000004294"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.121.318145"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25138"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25433"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.26227","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ppul.26227","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.26227","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T03:50:07Z","timestamp":1692330607000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.26227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":87,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1002\/ppul.26227"],"URL":"https:\/\/doi.org\/10.1002\/ppul.26227","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"2022-08-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}