{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T12:23:07Z","timestamp":1783686187399,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,28]],"date-time":"2022-12-28T00:00:00Z","timestamp":1672185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>E\u2010cigarette, or vaping, product use\u2010associated lung injury (EVALI) results from inhaling the aerosol of e\u2010cigarettes and has similar clinical features to coronavirus disease 2019 (COVID\u201019). EVALI case counts since the declaration of the COVID\u201019 pandemic is unknown.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective electronic health record chart review of adolescents hospitalized at one institution with EVALI was conducted. Clinical characteristics and hospital course of patients hospitalized during the pandemic were compared to those prepandemic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The clinical presentation of adolescents hospitalized prior\u2010to (<jats:italic>n<\/jats:italic>\u2009=\u200919) and during the COVID\u201019 pandemic (<jats:italic>n<\/jats:italic>\u2009=\u200922) were similar with respect to constitutional, respiratory, and gastrointestinal symptoms. All patients hospitalized during the pandemic were tested for COVID\u201019 at least once. Only one patient had a positive SARS\u2010CoV\u20102 RT\u2010PCR test result. Thirty\u2010one\u00a0out of 39 patients treated with corticosteroids had clinical improvement within 24\u2009h (79%). Patients hospitalized during the pandemic had a shorter median length of stay (5 vs. 7 days, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), and were less often discharged with home oxygen (1 vs. 6 patients, <jats:italic>p<\/jats:italic>\u2009=\u20090.04). Pulmonary function tests improved pre\u2010 to postcorticosteroid treatment and postcorticosteroid to follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Eliciting a history of vaping in adolescents presenting with constitutional, respiratory, and gastrointestinal symptoms is important to identify EVALI cases, which have continued throughout the COVID\u201019 pandemic. A shorter length of stay with less need for mechanical ventilation and home oxygen in adolescents hospitalized during the pandemic may reflect increased familiarity with EVALI characteristics. Corticosteroids led to clinical and pulmonary function improvement.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.26283","type":"journal-article","created":{"date-parts":[[2022,12,19]],"date-time":"2022-12-19T07:15:56Z","timestamp":1671434156000},"page":"949-958","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Clinical manifestations of EVALI in adolescents before and during the COVID\u201019 pandemic"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1907-8962","authenticated-orcid":false,"given":"Bayan","family":"Abdallah","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center Division of Pulmonology and Sleep Medicine  Dallas Texas USA"},{"name":"Children's Health System of Texas  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3675-4731","authenticated-orcid":false,"given":"Harin","family":"Lee","sequence":"additional","affiliation":[{"name":"University of Texas Southwestern Medical Center Medical School  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sitara M.","family":"Weerakoon","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at Houston School of Public Health, Dallas Campus  Dallas Texas USA"},{"name":"Center for Pediatric Population Health, University of Texas Health Science Center at Houston School of Public Health, Dallas Campus  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6685-2175","authenticated-orcid":false,"given":"Sarah E.","family":"Messiah","sequence":"additional","affiliation":[{"name":"University of Texas Health Science Center at Houston School of Public Health, Dallas Campus  Dallas Texas USA"},{"name":"Center for Pediatric Population Health, University of Texas Health Science Center at Houston School of Public Health, Dallas Campus  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa B.","family":"Harrell","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Texas Health Science Center at Houston (UTHealth)  Austin Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devika R.","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Texas Southwestern Medical Center Division of Pulmonology and Sleep Medicine  Dallas Texas USA"},{"name":"Children's Health System of Texas  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Centers for Disease Control and Prevention.\u00a0Youth and tobacco use.\u00a02022. 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