{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T14:42:24Z","timestamp":1776177744049,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Although inspiratory muscle training (IMT) has proven effective in adult rheumatic diseases, its impact on juvenile idiopathic arthritis (JIA) remains unexplored. The present study aimed to investigate the effects of IMT in children with JIA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty\u2010three children (13\u201318 years) with JIA were divided into two groups as exercise (<jats:italic>n<\/jats:italic>\u2009=\u200917) and control (<jats:italic>n<\/jats:italic>\u2009=\u200916). The exercise group performed IMT at home daily for 8 weeks. The initial IMT load was set as 60% of maximal inspiratory pressure (PI<jats:sub>max<\/jats:sub>) and increased by %10 of the initial load every 2 weeks. The control group received no additional intervention. Forced vital capacity (FVC), forced expiratory volume in 1 s (FEV<jats:sub>1<\/jats:sub>), FVC\/FEV<jats:sub>1<\/jats:sub>, PI<jats:sub>max<\/jats:sub>, and maximal expiratory pressure (PE<jats:sub>max<\/jats:sub>) were evaluated. Peak oxygen consumption (VO<jats:sub>2max<\/jats:sub>), metabolic equivalents (METs), and maximal heart rate were measured with cardiopulmonary exercise test. Functional capacity and quality of life were assessed with 6\u2010min walk distance and Pediatric Quality of Life Inventory 3.0 Arthritis Module. All participants were evaluated at baseline and post\u2010treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>FVC (\u2009\u2191\u20090.20 (95% CI: 0.07\/0.32) liters), FEV<jats:sub>1<\/jats:sub> (\u2009\u2191\u20090.14 (95% CI: 0.02\/0.25) liters), PI<jats:sub>max<\/jats:sub> (\u219119.11 (95% CI: 9.52\/28.71) cmH<jats:sub>2<\/jats:sub>O), PE<jats:sub>max<\/jats:sub> (\u219112.41 (95% CI: 3.09\/21.72) cmH<jats:sub>2<\/jats:sub>O), VO<jats:sub>2peak<\/jats:sub> (\u2191158.29 (95% CI: 63.85\/252.73) ml\/min), and METs (\u21910.92 (95% CI: 0.34\/1.49) [ml\/kg\/min]) significantly improved only in the exercise group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). The difference over time in FVC, FEV<jats:sub>1<\/jats:sub>, PI<jats:sub>max<\/jats:sub>, VO<jats:sub>2peak<\/jats:sub>, and METs were significantly higher in exercise group compared to control group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>IMT seems to be an effective option for improving respiratory functions and aerobic exercise capacity in JIA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.26783","type":"journal-article","created":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T13:15:28Z","timestamp":1701436528000},"page":"562-573","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["The effects of inspiratory muscle training on cardiorespiratory functions in juvenile idiopathic arthritis: A randomized controlled trial"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2465-7990","authenticated-orcid":false,"given":"Devrim Can","family":"Sarac","sequence":"first","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences Izmir Katip Celebi University Izmir Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2852-8910","authenticated-orcid":false,"given":"Deniz","family":"Bayraktar","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences Izmir Katip Celebi University Izmir Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6899-852X","authenticated-orcid":false,"given":"Derya","family":"Ozer Kaya","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences Izmir Katip Celebi University Izmir Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9877-3463","authenticated-orcid":false,"given":"Ozge","family":"Altug Gucenmez","sequence":"additional","affiliation":[{"name":"Clinic of Pediatric Rheumatology University of Health Sciences Dr. Behcet Uz Pediatric Diseases and Surgery Training and Research Hospital Izmir Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2217-076X","authenticated-orcid":false,"given":"Deran","family":"Oskay","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences Gazi University Ankara Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00332-8"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.4274\/balkanmedj.2017.0111"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2013.09.003"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-010-1548-5"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2014-306049"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0496(199712)24:6<444::AID-PPUL10>3.0.CO;2-8"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.14c09.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-021-00509-1"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002960050047"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003930200025"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-015-0053-5"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22893"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-018-4209-8"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009742.2015.1126345"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22897"},{"key":"e_1_2_9_17_1","unstructured":"FranklinE AnjumFIncentive Spirometer and Inspiratory Muscle Training.StatPearls. 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