{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:53:28Z","timestamp":1786978408207,"version":"build-2736575974"},"reference-count":51,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T00:00:00Z","timestamp":1707868800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In children, pulmonary fibrosis (PF) is an extremely unusual entity that can be observed in some types of interstitial lung disease (ILD). Defining whether ILD is accompanied by PF is important for targeted therapy. Algorithm for the diagnosis of PF in children is not clearly established. Besides, the clinical, radiological, and histological definitions commonly used to diagnose particularly the cases of idiopathic PF in adult patients, is not applicable to pediatric cases. However, a few studies conducted in children offer good exemplary\u00a0diagnostic approach to fibrosing ILD. Thorax high resonance computed tomography and\/or lung biopsy scanning can provide valuable information about PF. Another issue that has not been clearly established is when to start antifibrotic treatment in pediatric patients with PF. The objective of this current review is to provide a comprehensive overview of pediatric PF by drawing upon adult research, particularly focusing on the areas of uncertainty.<\/jats:p>","DOI":"10.1002\/ppul.26905","type":"journal-article","created":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T05:54:46Z","timestamp":1707890086000},"page":"1165-1174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fibrotic lung diseases in children"],"prefix":"10.1002","volume":"59","author":[{"given":"Birce","family":"Sunman","sequence":"first","affiliation":[{"name":"Department of Pediatric Pulmonology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nural","family":"Kiper","sequence":"additional","affiliation":[{"name":"Department of Pediatric Pulmonology Hacettepe University Faculty of Medicine Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.25356"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-8-24"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-5-22"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-021-04004-z"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11226736"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-023-05290-9"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8091312"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.55.091902.103810"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201903-0544CI"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/7757776"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.291085096"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950010307"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/ped.2010.0008"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12185"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-2652"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-15-43"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-1780"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201501-064OC"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2005230"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2589-7500(22)00173-X"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0193-2020"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.17.18384"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2018.06.013"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201807-1255ST"},{"issue":"64","key":"e_1_2_11_26_1","first-page":"5257","article-title":"Assessment of fibrosis in lung biopsies from the European childhood interstitial lung disease (chILD) registry","volume":"56","author":"Matthias Griese ES","year":"2020","journal-title":"Eur Respir J"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01512-2022"},{"issue":"5","key":"e_1_2_11_28_1","first-page":"343","article-title":"Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis","volume":"11","author":"Meyer KC","year":"2017","journal-title":"Expert Rev Respir Med"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.26627"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00143610"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1183\/16000617.0100-2017"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201611-2201PP"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201203-0513CI"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-022-01239-0"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.312095160"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2015-207349"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.23133"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22811"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI79100"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1312625"},{"key":"e_1_2_11_41_1","article-title":"Diffuse parenchymal lung disease caused by surfactant deficiency: dramatic improvement by azithromycin","volume":"2013","author":"Thouvenin G","year":"2013","journal-title":"Case Reports"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2011.05.009"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0136160"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2016.02.001"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0000000000002266"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-020-01452-5"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.708463"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-023-06623-7"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2020.05.557"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.26465"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjresp-2017-000212"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20970"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.26905","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T05:23:39Z","timestamp":1739251419000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.26905"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,14]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1002\/ppul.26905"],"URL":"https:\/\/doi.org\/10.1002\/ppul.26905","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,14]]},"assertion":[{"value":"2023-11-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}