{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:15:02Z","timestamp":1740104102139,"version":"3.37.3"},"reference-count":64,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T00:00:00Z","timestamp":1709596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Many ventilator\u2010dependent children have comorbid conditions including urinary tract disorders. We aimed to present a focused review of the literature describing the causes and management of urinary system problems in children with long\u2010term home mechanical ventilation. We performed a literature search in PubMed\/MEDLINE, Scopus, and Web of Science with keywords \u201cchildren,\u201d \u201chome mechanical ventilation,\u201d \u201curinary system,\u201d \u201curinary tract,\u201d \u201cneurogenic bladder,\u201d \u201cclean intermittent catheterization,\u201d \u201curinary tract infection,\u201d \u201curolithiasis,\u201d and \u201cacute kidney injury.\u201d We included original articles, reviews, guidelines, and case reports published in English. Ventilator\u2010dependent children may have neurogenic bladder\/bowel dysfunction which renders them prone to urinary tract infection, high bladder pressure, vesicoureteral reflux, hydronephrosis, and renal dysfunction. These children require bladder catheterization, medications affecting parasympathetic\/sympathetic nervous systems, or surgical procedures to prevent urinary infections, and to maintain continence and renal functions. However, bladder catheterization or surgical procedures like augmentation cystoplasty may also be complicated with urinary infections, urolithiasis, or urethral strictures. Urolithiasis frequency is also increased due to immobilization\u2010related hypercalciuria, hypocitraturia caused by antiepileptic drugs, urinary stasis, and urinary infections. On the other hand, mechanical ventilation can impair renal function by reduction of cardiac output, redistribution of intrarenal blood flow and stimulation of sympathetic and hormonal pathways. Children requiring long\u2010term invasive home mechanical ventilation may have other comorbid conditions, including urinary system diseases, which become manifest as these patients are being kept alive due to the advances in ventilation strategies. These children must be carefully observed for urological complications and managed accordingly to prevent kidney injury.<\/jats:p>","DOI":"10.1002\/ppul.26947","type":"journal-article","created":{"date-parts":[[2024,3,5]],"date-time":"2024-03-05T14:08:52Z","timestamp":1709647732000},"page":"2103-2112","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Causes and management of urinary system problems in children on long\u2010term home invasive mechanical ventilation"],"prefix":"10.1002","volume":"59","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5901-7398","authenticated-orcid":false,"given":"Alper","family":"Soylu","sequence":"first","affiliation":[{"name":"Department of Pediatric Nephrology Dokuz Eyl\u00fcl University Medical Faculty Bal\u00e7ova Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9959-881X","authenticated-orcid":false,"given":"Salih","family":"Kavukcu","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology Dokuz Eyl\u00fcl University Medical Faculty Bal\u00e7ova Izmir Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,3,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/apa.15177"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201602-0276ST"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/21548331.2021.1988608"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpc.15506"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-008-0764-7"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2022.04.011"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.25245"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22783"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24211"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-019-02743-5"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0000000000000625"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-022-04235-5"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000138847.14680.7d"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2013.46"},{"key":"e_1_2_7_16_1","article-title":"Long\u2010term bladder management by intermittent catheterisation in adults and children","volume":"4","author":"Moore KN","year":"2007","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2015.12.012"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2433-1"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22248"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22751"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.22560"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2018.04.010"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2015.195"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2019.10.044"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.24928"},{"key":"e_1_2_7_26_1","unstructured":"RadmayrC BogaertG BurguB et al. European Association of Urology Guideline on Pediatric Urology.https:\/\/d56bochluxqnz.cloudfront.net\/documents\/full-guideline\/EAU-Guidelines-on-Paediatric-Urology-2023.pdf"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.08.008"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.120112"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)37517-1"},{"key":"e_1_2_7_30_1","first-page":"31","article-title":"Comparison and overview of currently available neurotoxins","volume":"7","author":"Walker TJ","year":"2014","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.116.012658"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.28559"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2015.08.018"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPB.0000000000001055"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/ans.16736"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-2003-1823"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)68861-1"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000078015.55801.52"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000000555"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41393-021-00679-5"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1086\/650482"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2016.01.002"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2019.2504"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.10.092"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1505-23"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.4111\/icu.2017.58.S1.S54"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-018-2345-0"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.2014.63"},{"key":"e_1_2_7_49_1","first-page":"11374","article-title":"Effects of non\u2010invasive ventilation on renal and endothelial function in patients with respiratory failure","volume":"24","author":"Lai S","year":"2020","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2002.31419"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1159\/000491557"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2015.1419"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2019.09.021"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)36262-9"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2011.02.018"},{"key":"e_1_2_7_56_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2006.07.003"},{"key":"e_1_2_7_57_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2012.0063"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yapd.2020.03.004"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.02.2562"},{"key":"e_1_2_7_60_1","first-page":"134","article-title":"Hypocitraturia: pathophysiology and medical management","volume":"11","author":"Zuckerman JM","year":"2009","journal-title":"Rev Urol"},{"key":"e_1_2_7_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-007-0740-7"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-007-9292-9"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2021.05.006"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1159\/000513074"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2008.01.002"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.26947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T10:03:05Z","timestamp":1721988185000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.26947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,5]]},"references-count":64,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1002\/ppul.26947"],"URL":"https:\/\/doi.org\/10.1002\/ppul.26947","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"type":"print","value":"8755-6863"},{"type":"electronic","value":"1099-0496"}],"subject":[],"published":{"date-parts":[[2024,3,5]]},"assertion":[{"value":"2023-08-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}