{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T02:56:50Z","timestamp":1785553010530,"version":"3.56.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T00:00:00Z","timestamp":1712620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The polysomnography (PSG) is the gold\u2010standard for obstructive sleep apnea (OSA) syndrome diagnosis and assessment under positive airway pressure (PAP) therapies in children. Recently, an innovative digital medicine solution, including a mandibular jaw movement (MJM) sensor coupled with\u00a0automated analysis, has been validated as an alternative to PSG for pediatric application.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to assess the reliability of MJM\u00a0automated analysis for the assessment of residual apnea\/hypopnea events during sleep in children with OSA treated with noninvasive ventilation (NIV) or continuous PAP\u00a0(CPAP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this open\u2010label prospective non\u2010randomized multicentric trial, we included children aged from 5 to 18 years with a diagnosis of severe OSA. The children underwent in\u2010laboratory PSG with simultaneous MJM monitoring and at\u2010home recording with MJM monitoring 3 months later. Agreement between PSG and MJM analysis in measuring the residual apnea\u2010hypopnea index (AHI) was evaluated by the Bland\u2212Altman method. The treatment effect on residual AHI was estimated for both PSG and MJM analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fifteen (60% males) children were included with a median age of 12 years [interquartile range 8\u221215]. Two (17%) were ventilated with NIV and 13 (83%) with CPAP. There was a good agreement between MJM\u2010AHI and PSG\u2010AHI with a median bias of \u22120.25 (95% CI: \u22123.40 to +2.04) events\/h. The reduction in AHI under treatment was consistently significant across the three measurement methods: in\u2010laboratory PSG\u00a0and MJM recordings in the laboratory and at home.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Automated analysis of MJM is a highly reliable alternative method to assess residual events in a small population treated with PAP therapies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ppul.27005","type":"journal-article","created":{"date-parts":[[2024,4,9]],"date-time":"2024-04-09T18:55:34Z","timestamp":1712688934000},"page":"1905-1911","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Analysis of mandibular jaw movements to assess ventilatory support management of children with obstructive sleep apnea syndrome treated with positive airway pressure therapies"],"prefix":"10.1002","volume":"59","author":[{"given":"Julie","family":"Cassibba","sequence":"first","affiliation":[{"name":"Pediatric Department Grenoble Alpes University Hospital Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Aubertin","sequence":"additional","affiliation":[{"name":"Pediatric Pulmonology Department and Reference Center for Rare Respiratory Diseases RespiRare, Armand Trousseau Hospital, APHP Sorbonne University Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8536-7300","authenticated-orcid":false,"given":"Jean Benoit","family":"Martinot","sequence":"additional","affiliation":[{"name":"Sleep Laboratory, CHU University Catholique of Louvain (UCL) Namur Site Sainte\u2010Elisabeth Namur Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nam","family":"Le Dong","sequence":"additional","affiliation":[{"name":"Sunrise Namur Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eglantine","family":"Hullo","sequence":"additional","affiliation":[{"name":"Pediatric Department Grenoble Alpes University Hospital Grenoble France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6417-382X","authenticated-orcid":false,"given":"Nicole","family":"Beydon","sequence":"additional","affiliation":[{"name":"Sorbonne\u2010Universit\u00e9, H\u00f4pital Trousseau, Unit\u00e9 Fonctionnelle de Physiologie \u2010 Explorations Fonctionnelles Respiratoires et du Sommeil Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey","family":"Dupont\u2010Ath\u00e9nor","sequence":"additional","affiliation":[{"name":"Pediatric Pulmonology Department and Reference Center for Rare Respiratory Diseases RespiRare, Armand Trousseau Hospital, APHP Sorbonne University Paris 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