{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:06:40Z","timestamp":1791893200673,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Acute bronchiolitis is a pressing public health concern, leading to numerous infant hospitalizations worldwide annually. The notable decrease in bronchiolitis hospitalizations during the COVID\u201019 pandemic sparked concerns about a potential resurgence post\u2010pandemic. Questions also arose about the severity of post\u2010pandemic cases compared to prepandemic ones. This study aimed to compare bronchiolitis severity before and after the COVID\u201019 pandemic, alongside changes in the epidemiology of bronchiolitis viral agents.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective analysis of medical records concerning infants under 12 months hospitalized for acute bronchiolitis in our pediatric pulmonology department over a period of 5 years: 2 pre\u2010COVID years (2018\u22122020), the COVID year (2020), and 2 post\u2010COVID years (2021\u22122023). Clinical and laboratory data were collected using standardized forms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Hospital admissions exhibited comparable rates pre\u2010 and post\u2010COVID but witnessed a decline during the COVID period. Post\u2010COVID, bronchiolitis severity increased, with longer hospitalization durations (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and increased oxygen therapy (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), coinciding with a surge in the prevalence of RSV infections (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01). Patients testing positive for RSV were significantly younger (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005) and exhibited more severe symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and Conclusion<\/jats:title>\n                    <jats:p>This study reveals a significant increase in bronchiolitis severity and a rise in RSV cases following the COVID pandemic. The implementation of preventive measures such as nirsevimab is crucial to alleviate the burden of respiratory illnesses in vulnerable populations. Continued vigilance and research are needed to address the evolving challenges of bronchiolitis in the post\u2010COVID era.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.27172","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T09:46:26Z","timestamp":1720691186000},"page":"3197-3203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Bronchiolitis: Increased severity in the post\u2010COVID\u201019 era"],"prefix":"10.1002","volume":"59","author":[{"given":"Victorine","family":"Boccard","sequence":"first","affiliation":[{"name":"Sorbonne Universit\u00e9, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP), H\u00f4pital Trousseau, Service de Pneumologie P\u00e9diatrique, Centre de R\u00e9f\u00e9rence des Maladies Respiratoires Rares RespiRare Paris France"},{"name":"Sorbonne Universit\u00e9, Centre de Recherche Saint\u2010Antoine (CRSA), Inserm UMR_S938 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blandine","family":"Prevost","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP), H\u00f4pital Trousseau, Service de Pneumologie P\u00e9diatrique, Centre de R\u00e9f\u00e9rence des Maladies Respiratoires Rares RespiRare Paris France"},{"name":"Sorbonne Universit\u00e9, Centre de Recherche Saint\u2010Antoine (CRSA), Inserm UMR_S938 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Denamur","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP), H\u00f4pital Trousseau, Service de Pneumologie P\u00e9diatrique, Centre de R\u00e9f\u00e9rence des Maladies Respiratoires Rares RespiRare Paris France"},{"name":"Sorbonne Universit\u00e9, Centre de Recherche Saint\u2010Antoine (CRSA), Inserm UMR_S938 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elora","family":"Peulier\u2010Maitre","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP), H\u00f4pital Trousseau, Service de Pneumologie P\u00e9diatrique, Centre de R\u00e9f\u00e9rence des Maladies Respiratoires Rares RespiRare Paris France"},{"name":"Sorbonne Universit\u00e9, Centre de Recherche Saint\u2010Antoine (CRSA), Inserm UMR_S938 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5149-7975","authenticated-orcid":false,"given":"Nadia","family":"Nathan","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP), H\u00f4pital Trousseau, Service de Pneumologie P\u00e9diatrique, Centre de R\u00e9f\u00e9rence des Maladies Respiratoires Rares RespiRare Paris France"},{"name":"Sorbonne Universit\u00e9, Laboratory of Childhood Genetic Diseases, Inserm UMR_S933 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7026-7523","authenticated-orcid":false,"given":"Harriet","family":"Corvol","sequence":"additional","affiliation":[{"name":"Sorbonne Universit\u00e9, Assistance Publique\u2010H\u00f4pitaux de Paris (AP\u2010HP), H\u00f4pital Trousseau, Service de Pneumologie P\u00e9diatrique, Centre de R\u00e9f\u00e9rence des Maladies Respiratoires Rares RespiRare Paris France"},{"name":"Sorbonne Universit\u00e9, Centre de Recherche Saint\u2010Antoine (CRSA), Inserm UMR_S938 Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01016-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30951-5"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-017-0031-8"},{"key":"e_1_2_9_5_1","unstructured":"Sant\u00e9 Publique France. 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