{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T11:01:28Z","timestamp":1771412488327,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate the ability of the criteria \u201cAt\u2010risk for PARDS\u201d to identify patients with acute respiratory infection hospitalized outside the pediatric intensive care unit (PICU) who are at high risk of developing pediatric acute respiratory distress syndrome (PARDS) and describe the timing for the identification. The secondary aim was to explore clinical outcome differences between patients with and without risk for PARDS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted an observational prospective cohort study from June to August 2019. Children under 15 years old hospitalized in a pediatric ward due to an acute respiratory tract infection were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main Results<\/jats:title>\n                    <jats:p>\n                      A total of 177 patients with a median age of 12 (IQR 5; 25) months were included. Registered data included demographics, respiratory support, at\u2010risk for PARDS and PARDS diagnosis according to PALICC consensus. PICU admission, hospital length of stay (LOS) and intrahospital mortality were the outcomes compared between children with and without risk for PARDS. The at\u2010risk criteria, within 48\u2009h of admission, showed an overall accuracy, sensitivity, and specificity of 82.5%, 100%, and 81.9% respectively, to detect patients that progress to PARDS. The at\u2010risk for PARDS criteria was met in 37 cases (20.9%), which also were more likely to developed PARDS (6\/37 [16.2%] vs. 0\/140 [0%];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), had higher admission to PICU (16\/37 [43.2%] vs. 0 [0%];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and hospital LOS (7 [6; 12] days vs. 5 [3\u22126] days;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), compared with the group without at\u2010risk for PARDS.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The at\u2010risk for PARDS criteria within 48\u2009h of admission demonstrated an adequate ability to identify patients with a respiratory infection at increased risk of developing PARDS. Patients who met the at\u2010risk for PARDS criteria before PICU admission presented with unfavorable clinical outcomes compared with those without risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71146","type":"journal-article","created":{"date-parts":[[2025,5,28]],"date-time":"2025-05-28T02:32:23Z","timestamp":1748399543000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes of Children Meeting the At\u2010Risk for PARDS Criteria Before PICU Admission: A Single\u2010Center Study"],"prefix":"10.1002","volume":"60","author":[{"given":"Fernando D.","family":"Bustos\u2010Gajardo","sequence":"first","affiliation":[{"name":"Pediatric Intensive Care unit Hospital Dr. V\u00edctor R\u00edos Ru\u00edz Los \u00c1ngeles Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Adasme","family":"Jeria","sequence":"additional","affiliation":[{"name":"Exercise and Rehabilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences Universidad Andres Bello Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Piraino","sequence":"additional","affiliation":[{"name":"Deparment of Anesthesia, Division of Critical Care McMaster University Hamilton Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9337-1254","authenticated-orcid":false,"given":"Pablo","family":"Cruces","sequence":"additional","affiliation":[{"name":"Departamento de Pediatr\u00eda Unidad de Paciente Cr\u00edtico Pedi\u00e1trico, Hospital El Carmen de Maip\u00fa Santiago Chile"},{"name":"Centro de Investigaci\u00f3n de Medicina Veterinaria, Escuela de Medicina Veterinaria, Facultad de Ciencias de la Vida Universidad Andres Bello Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8338-0488","authenticated-orcid":false,"given":"L. Felipe","family":"Damiani","sequence":"additional","affiliation":[{"name":"Escuela de Ciencias de la Salud, Departamento de Kinesiolog\u00eda, Facultad de Medicina Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"},{"name":"CardioREspirAtory Reaserch Laboratory (CREAR) Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2462"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(18)30344-8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000000432"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000003161"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000005287"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001812"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medin.2021.10.006"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2006.00179.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.308.6943.1552"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.309.6947.102"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000001836"},{"issue":"4","key":"e_1_2_11_13_1","first-page":"317","article-title":"Acute Lung Injury in Pediatric Intensive Care in Australia and New Zealand: A Prospective, Multicenter, Observational Study","volume":"8","author":"Erickson S.","year":"2007","journal-title":"Pediatric Critical Care Medicine: A Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1676133"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-018-5286-6"}],"container-title":["Pediatric Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.71146","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ppul.71146","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ppul.71146","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T10:03:31Z","timestamp":1771409011000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ppul.71146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1002\/ppul.71146"],"URL":"https:\/\/doi.org\/10.1002\/ppul.71146","archive":["Portico"],"relation":{},"ISSN":["8755-6863","1099-0496"],"issn-type":[{"value":"8755-6863","type":"print"},{"value":"1099-0496","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"2024-09-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71146"}}