{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:00:59Z","timestamp":1788314459120,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T00:00:00Z","timestamp":1752105600000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Congenital pulmonary airway malformations (CPAMs) are rare developmental lung anomalies. The optimal management of asymptomatic neonates remains a subject of debate. This study presents the experience of a Tunisian tertiary referral in the prenatal and postnatal diagnosis and management of CPAM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a 5\u2010year retrospective descriptive study (2019\u20132024) study in the Neonatology and Intensive Care Unit of the Maternity and Neonatology Center of Tunis. All neonates diagnosed with CPAM were included.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirteen neonates with CPAM were managed. The mean maternal age was 31.4 yearsAntenatal diagnosis was made in 77% (10\/13) of cases. Polyhydramnios was observed in two cases, hydrops fetalis in one, and dextrocardia in one. No antenatal interventions were performed. Cesarean section was performed in 10 cases, including four for fetal indications. Three neonates developed severe respiratory distress requiring mechanical ventilation; two died before surgical intervention, and one underwent lobectomy via thoracotomy at 9 months via thoracotomy, with an uneventful recovery. Histopathological examination confirmed type II CPAM. The remaining 10 patients were managed conservatively, with favorable outcomes during a mean follow\u2010up of 4 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The management of CPAM requires a multidisciplinary team and begins in the antenatal period. Even asymptomatic patients require close and prolonged monitoring, as complications may arise later. Surgical intervention should be considered on a case\u2010by\u2010case basis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71188","type":"journal-article","created":{"date-parts":[[2025,7,10]],"date-time":"2025-07-10T12:45:04Z","timestamp":1752151504000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Congenital Pulmonary Airway Malformations: Experience of a Tunisian Tertiary Referral Center Over a Five\u2010Year Period"],"prefix":"10.1002","volume":"60","author":[{"given":"Hajer","family":"Chourou","sequence":"first","affiliation":[{"name":"Neonatal Medicine and Intensive Care Unit Maternity and Neonatology Center of Tunis Tunis Tunisia"},{"name":"Faculty of Medicine of Tunis University of Tunis El Manar Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8067-1764","authenticated-orcid":false,"given":"Rim","family":"Ben Aziza","sequence":"additional","affiliation":[{"name":"Neonatal Medicine and Intensive Care Unit Maternity and Neonatology Center of Tunis Tunis Tunisia"},{"name":"Faculty of Medicine of Tunis University of Tunis El Manar Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manel","family":"Bourcheda","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis University of Tunis El Manar Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosra","family":"Sdiri","sequence":"additional","affiliation":[{"name":"Neonatal Medicine and Intensive Care Unit Maternity and Neonatology Center of Tunis Tunis Tunisia"},{"name":"Faculty of Medicine of Tunis University of Tunis El Manar Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houyem","family":"Khiari","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis University of Tunis El Manar Tunis Tunisia"},{"name":"Preventive Medicine Department, Salah Azaiez Institute University of Tunis El Manar Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samia","family":"Kacem","sequence":"additional","affiliation":[{"name":"Neonatal Medicine and Intensive Care Unit Maternity and Neonatology Center of Tunis Tunis Tunisia"},{"name":"Faculty of Medicine of Tunis University of Tunis El Manar Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Said","family":"Jlidi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis University of Tunis El Manar Tunis Tunisia"},{"name":"Department of Pediatric Surgery \u201cB\u201d Children Hospital Tunis 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