{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:21:05Z","timestamp":1785208865031,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T00:00:00Z","timestamp":1754611200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007914","name":"University of Texas Southwestern Medical Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007914","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Rationale<\/jats:title>\n                    <jats:p>Extreme preterm birth is a recognized risk factor for reduced pulmonary function over the lifespan. However, data are lacking in U.S.\u2010born adults and in multiethnic populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To comprehensively evaluate lung function in adolescents and young adults born premature, and to assess for potential impact of neonatal, racial\/ethnic, and socioeconomic risk factors on long\u2010term lung function.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Preterm participants aged 12\u201340 years of age were recruited from the Parkland Hospital Neonatal ICU Registry (Dallas County, Texas). Preterm and term\u2010born participants completed pulmonary function testing including spirometry, lung volumes, diffusion capacity, and respiratory muscle forces, using Global Lung Initiative race\u2010neutral reference equations. Influence of racial\/ethnic background, neonatal factors, and socioeconomic ratings were assessed for preterm participants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Preterm participants (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009105; gestational age 29.5\u2009\u00b1\u20092.5 weeks; current age 26\u2009\u00b1\u20096\u2009yrs) were significantly more likely than term participants (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200948; gestational age 39.2\u2009\u00b1\u20091.1 weeks; current age 29\u2009\u00b1\u20097\u2009yrs) to have an obstructive or restrictive ventilatory defect (34.4% vs 14.6%, OR 3.06, 95% CI 1.26\u20137.93), reduced diffusion capacity (16.4% vs 2.1%, OR 9.18, 95% CI 1.47\u201398.3), and impaired respiratory muscle strength (27.7% vs 4.4%, OR 8.22, 95% CI 2.10\u201336.2). Neonatal risk factors included history of bronchopulmonary dysplasia and lower weight for gestational age percentile. Lung function was worse in preterm\u2010born Non\u2010Hispanic Black participants compared to preterm\u2010born Hispanic White participants, which could not be explained by available neonatal or socioeconomic factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>While most moderately to extremely preterm\u2010born individuals have normal lung function, obstructive and restrictive ventilatory defects, reduced diffusion capacity, and impaired respiratory muscle strength are common.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71226","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T11:48:36Z","timestamp":1754653716000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Lung Function in a Multiethnic U.S. Cohort of Adolescents and Adults Born Preterm in the New BPD Era"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4651-6016","authenticated-orcid":false,"given":"Nataly J.","family":"Sanchez\u2010Solano","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Texas Southwestern Medical Center  Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9506-6162","authenticated-orcid":false,"given":"Tyler J.","family":"Wall","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Texas Southwestern Medical Center  Texas USA"},{"name":"Department of Internal Medicine University of Texas Southwestern Medical Center  Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7471-5488","authenticated-orcid":false,"given":"Gregory P.","family":"Barton","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Texas Southwestern Medical Center  Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8791-5969","authenticated-orcid":false,"given":"Dan M.","family":"Dane","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Texas Southwestern Medical Center  Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1995-1407","authenticated-orcid":false,"given":"Connie C. 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