{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T16:04:04Z","timestamp":1771430644875,"version":"3.50.1"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Reproductive health (RH) has become increasingly significant with the growing population of adults with cystic fibrosis (CF). We aimed to investigate the knowledge, attitudes, and behaviors of adult CF patients regarding RH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this prospective observational study, participants aged\u2009\u2265\u200918 attending an outpatient clinic completed a RH questionnaire face\u2010to\u2010face with the same respiratory physician.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 100 patients were included in the study (men\/women: 54\/46), with a median age of 22 years (IQR\u2009=\u200919\u201327). Among the patients 15 (15%) had a partner, 84 (84%) were single, and 1 (1%) was divorced. Six (6%) had children. Of the 40 patients who planned to have a child, 34 (85%) intended to receive genetic counseling. All patients were sexually active; however, 90 (90%) did not use any contraception method. Anti\u2010M\u00fcllerian hormone (AMH) levels were obtained from 38 (82.6%) females, while only 7 (13%) males agreed to perform a spermiogram, 17 (31.5%) males had a scrotal ultrasound. Approximately 68.5% of the male participants were unaware of or misunderstood their infertility risk. The source of information about RH in CF did not affect the level of concern about infertility (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). However, believing that their knowledge about the relationship between the disease and infertility was sufficient did affect their level of concern (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings highlight that accurate knowledge about RH is insufficient among CF patients. More than half of the male patients who underwent sperm analysis did not want to share their results with healthcare providers. This finding is striking because more than 95% of male CF patients are known to be infertile due to vas deferens abnormalities. Our findings suggest that the follow\u2010up of adult CF patients primarily focuses on the respiratory system and other severely affected organs, while RH remains somewhat overlooked. This is significant as it highlights the patients\u2019 insufficient knowledge on the topic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71247","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T07:01:20Z","timestamp":1755154880000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Knowledge, Attitudes, and Behaviors of Cystic Fibrosis Patients on Reproductive Health in Turkiye"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9438-6052","authenticated-orcid":false,"given":"Hande","family":"Yuce Ozdemir","sequence":"first","affiliation":[{"name":"Department of Chest Diseases Hacettepe University School of Medicine Ankara Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7000-7580","authenticated-orcid":false,"given":"Sezcan","family":"Mumusoglu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Hacettepe University School of Medicine Ankara Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7475-3775","authenticated-orcid":false,"given":"Ali Fuat","family":"Kalyoncu","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases, Division of Allergy and Clinical Immunology Hacettepe University School of Medicine Ankara Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6250-2100","authenticated-orcid":false,"given":"Ebru","family":"Damadoglu","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases, Division of Allergy and Clinical Immunology Hacettepe University School of Medicine Ankara Turkiye"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.8120"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2020.07.009"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0000000000001009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2023.10.023"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/life13071545"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(14)70231-0"},{"issue":"1","key":"e_1_2_10_8_1","first-page":"S75","article-title":"Family\u2010Building and Parenting Considerations for People With Cystic Fibrosis","volume":"57","author":"Kazmerski T. 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