{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,8]],"date-time":"2025-12-08T08:19:46Z","timestamp":1765181986051,"version":"3.46.0"},"reference-count":40,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:00:00Z","timestamp":1758153600000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Pulmonology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Exercise\u2010induced bronchoconstriction (EIB) is common among adolescents and athletes. While typically assessed with spirometry, oscillometry may offer complementary insights. This cross\u2010sectional study examined how fractional exhaled nitric oxide (FeNO) and symptoms relate to postexercise airway responses assessed via spirometry and oscillometry, and whether these associations differ between nonathletes and athletes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Subsamples from two adolescent cohorts (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009241; 143 nonathletes, 98 athletes) completed questionnaires, FeNO measurements, and an EIB test using spirometry, by change in forced expiratory volume in 1\u2009s (\u2206FEV\n                      <jats:sub>1<\/jats:sub>\n                      ), and oscillometry, by change in resistance and reactance at 5\u2009Hz (\u2206R\n                      <jats:sub>5<\/jats:sub>\n                      , \u2206X\n                      <jats:sub>5<\/jats:sub>\n                      ). Correlations were assessed using Spearman's rank; logistic regression evaluated associations between elevated FeNO and EIB; linear regression explored links between symptoms and postexercise airway responses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      EIB was detected in 70 participants via spirometry (\u2206FEV\n                      <jats:sub>1<\/jats:sub>\n                      \u2009\u2264\u2009\u221210%), 81 via oscillometry (\u2206R\n                      <jats:sub>5<\/jats:sub>\n                      \u2009\u2265\u200925%), and 37 by both. Among nonathletes, FeNO was weakly correlated with \u2206FEV\n                      <jats:sub>1<\/jats:sub>\n                      (\n                      <jats:italic>r<\/jats:italic>\n                      <jats:sub>\n                        <jats:italic>s<\/jats:italic>\n                      <\/jats:sub>\n                      \u2009=\u2009\u22120.17,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04), \u2206R\n                      <jats:sub>5<\/jats:sub>\n                      (0.35,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), and \u2206X\n                      <jats:sub>5<\/jats:sub>\n                      (\u22120.25,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005). Elevated FeNO (&gt;\u200920 parts per billion) was associated with EIB by \u2206FEV\n                      <jats:sub>1<\/jats:sub>\n                      (aOR 2.54, 95% CI: 1.05\u20136.12) and \u2206R\n                      <jats:sub>5<\/jats:sub>\n                      (aOR 3.05, 95% CI: 1.18\u20137.9). Respiratory symptoms also related to postexercise airway responses in nonathletes. In contrast, no such associations were observed in athletes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In nonathletes, elevated FeNO and symptoms can indicate who needs EIB testing. These indicators were less predictive in athletes, emphasizing the value of objective assessment. Oscillometry was complementary to spirometry to assess EIB and a combination of methods might be more informative.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ppul.71296","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T15:07:50Z","timestamp":1758208070000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Postexercise Airway Responses by Spirometry and Oscillometry in Nonathlete and Athlete Adolescents"],"prefix":"10.1002","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3185-3316","authenticated-orcid":false,"given":"Karin","family":"Ersson","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, Clinical Physiology Uppsala University Uppsala Sweden"},{"name":"Department of Women's and Children's Health, Physiotherapy Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kjell","family":"Alving","sequence":"additional","affiliation":[{"name":"Department of Women's and Children's Health, Paediatrics Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margareta","family":"Emtner","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Respiratory, Allergy and Sleep Research Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christer","family":"Janson","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Respiratory, Allergy and Sleep Research Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Johansson","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Clinical Physiology Uppsala University Uppsala Sweden"},{"name":"Department of Women's and Children's Health, Physiotherapy Uppsala University Uppsala Sweden"},{"name":"Department of Medical Sciences, Respiratory, Allergy and Sleep Research Uppsala University Uppsala Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Malinovschi","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Clinical Physiology Uppsala University Uppsala 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